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Association Between Igf- 1 Gene Polymorphisms And Body Weight In Nigeria Locally Adapted Turkeys

The insulin-like growth factor 1 (IGF-1) gene polymorphism plays important roles in development, growth and reproduction. Genetic intervention for the improvement o f Nigeria locally adapted turkeys based on growth rate and higher mature weight is important. This study was aimed at investigating the...

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Published: 2018
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/10782
042 |a dc 
720 |a Oyewola, K. A.  |e author 
720 |a Osaiyuwu, O.H.  |e author 
720 |a Fijabi, O.E.  |e author 
720 |a Shobanke, I.A.  |e author 
720 |a Nwokorie, G.I.  |e author 
720 |a Ewuola, K.M.  |e author 
260 |c 2018 
520 |a The insulin-like growth factor 1 (IGF-1) gene polymorphism plays important roles in development, growth and reproduction. Genetic intervention for the improvement o f Nigeria locally adapted turkeys based on growth rate and higher mature weight is important. This study was aimed at investigating the association between IGF-1 gene polymorphism and body weights in Nigeria locally adapted turkeys using PCR-RFLP method. Fifty poults were randomly selected for DNA analysis at 10 weeks. Zymo Miniprep kit was used for genomic DNA extraction from blood samples and 529bp fragment o f intron 2 o f IGF-1 gene was amplified. The genetic structure o f the population was analysed using POPGENE 32 software. Association o f the genotypes with body weight was evaluated using the General linear model of SAS 9.2. The enzyme digested products revealed A and B alleles with frequencies o f 0.61 and 0.39 respectively. Two genotypes A A (0.38) and AB (0.62) were detected. Chi-square test (0.001830) for Hardy-Weinberg equilibrium showed that the population sampled was not in equilibrium for the gene investigated. Also, significant association was not observed between IGF-1 polymorphs and body weight at 4, 8 and 12 weeks o f age in Nigeria locally adapted turkeys. 
024 8 |a https://repository.ui.edu.ng/handle/123456789/10782 
653 |a DNA 
653 |a Hardy-Weinberg equilibrium 
653 |a Improvement 
653 |a PCR-RFLP 
653 |a Polymorphs. 
245 0 0 |a Association Between Igf- 1 Gene Polymorphisms And Body Weight In Nigeria Locally Adapted Turkeys