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Challenges and prospects of neoadjuvant chemotherapy for gynaecologic malignancies in resource-limited settings.

Administration of chemotherapeutic agents followed by interval debulking surgery has been reported to be non-inferior to primary debulking surgery (PDS) and adjuvant chemotherapy. Limitation of human and nonhuman facilities for optimal surgical intervention makes Neoadjuvant chemotherapy (NACT) a de...

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Published: 2021
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/11812
042 |a dc 
720 |a Oluwasola, T. A. O.  |e author 
260 |c 2021 
520 |a Administration of chemotherapeutic agents followed by interval debulking surgery has been reported to be non-inferior to primary debulking surgery (PDS) and adjuvant chemotherapy. Limitation of human and nonhuman facilities for optimal surgical intervention makes Neoadjuvant chemotherapy (NACT) a desirable alternative in resource-limited settings. NACT is gradually becoming an acceptable alternative in centers with limited facilities for comprehensive PDS. Moreover, some recent studies have described NACT as being non- inferior to the gold standard of PDS although it is important to note that strict patient selection remains an important criterion and serve as the hallmark for the success of NACT This review aimed to explore the essence of NACT for gynecological malignancies, its challenges as well as prospects for resource-limited settings 
024 8 |a 2543-148X 
024 8 |a ui_art_oluwasola_challenges_2021 
024 8 |a Tropical Journal of Obstetrics & Gynaecology 38 (3), pp. 186 – 197 
024 8 |a https://repository.ui.edu.ng/handle/123456789/11812 
653 |a Adjuvant 
653 |a Adjunctive 
653 |a Chemotherapy 
653 |a Neoadjuvant 
653 |a Resource-Limited Setting 
245 0 0 |a Challenges and prospects of neoadjuvant chemotherapy for gynaecologic malignancies in resource-limited settings.