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Serum levels of vitamin D in male partners of women with infertility in a tertiary hospital in Nigeria.

Globally infertility affects 8-12% of couples, with male and female causes contributing equally. Micronutrient's deficiency such as vitamin D has been implicated as a cause of infertility in animal studies, there is therefore the need to evaluate its role in humans. This study determined serum level...

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Published: 2023-01
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/11869
042 |a dc 
720 |a Bamgboye, A. E.  |e author 
720 |a Ogunbode, O.O.  |e author 
720 |a Arowojolu, A.O  |e author 
260 |c 2023-01 
520 |a Globally infertility affects 8-12% of couples, with male and female causes contributing equally. Micronutrient's deficiency such as vitamin D has been implicated as a cause of infertility in animal studies, there is therefore the need to evaluate its role in humans. This study determined serum levels of vitamin D in males who were partners of patients presenting with infertility. This was a prospective cross- sectional study involving 170 consenting male partners of women presenting with infertility at the University College Hospital (UCH), Ibadan. A structured questionnaire was administered while blood sample and semen were collected for serum vitamin D assay and seminal fluid analysis (SFA) analysis. The data was entered into the Statistical Package for Social Sciences version 21 and statistical significance was set at less than 5%. Eighty-four (49.4%) participants had at least one abnormal parameter on SFA. The mean vitamin D level was higher in participants with normal SFA (34.4+12.6ng/ml) compared with abnormal SFA (32.8 + 15ng/ml). None of the participants had vitamin D deficiency, however the prevalence of vitamin D insufficiency among participants with abnormal and normal SFA was 62.5 % and 37.5% and this was statistically significant. (p = 0.01). Sperm progressive motility was the only SFA parameter associated with serum Vitamin D levels. (p-value = 0.03). This study showed that vitamin D insufficiency is associated with male infertility, therefore it may be added as an investigation for men with infertility and Vitamin D supplement be given where insufficiency or deficiency are noted. 
024 8 |a 1117-4153 
024 8 |a ui_art_bamigboye_serum_2023 
024 8 |a Tropical Journal of Health Sciences 30(1), pp.6-11 
024 8 |a https://repository.ui.edu.ng/handle/123456789/11869 
653 |a Infertility 
653 |a Seminal Fluid Analysis 
653 |a Vitamin D 
653 |a Micronutrients 
653 |a Male Factor 
245 0 0 |a Serum levels of vitamin D in male partners of women with infertility in a tertiary hospital in Nigeria.