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Comparison of the Calf Thymus DNA Binding Interactions of 5-hydroxymethylfurfural and its Synthesized Derivative, 5, 5’[oxy-bis(methylene)]bis-2-furfural: Experimental, DFT and Docking Studies.
In this study, the in vitro DNA-binding interactions of the food/drug additive, 5-hydroxymethylfurfural (HMF) and its major degradant, 5, 5’[oxy-bis(methylene)]bis-2-furfural (OBMF) were investigated. OBMF was synthesized and characterized using IR, NMR and mass spectrometry. Photometric titrations...
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2023
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