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Two New phytoecdysteroids from sphenocentrum jollyanum pierre root
The crude methanol extract of Sphenocentrum jollyanum root exhibited 98% and 80% antimicrobial activity against Aspergillus fumigatus Pinh and Vancomycin resistant enterococcus (VRE) at a concentration of 200 μg/mL, with ICso 11.45 and 12.95 μg/mL, respectively. The ethyl acetate fraction of methano...
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2019
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12134 | ||
| 042 | |a dc | ||
| 720 | |a Ajayi, T. O. |e author | ||
| 720 | |a Srivedavyasasri, R. |e author | ||
| 720 | |a Nyong, E. E. |e author | ||
| 720 | |a Odeniyi, M. A. |e author | ||
| 720 | |a Moody, J. O. |e author | ||
| 720 | |a Ross, S. A. |e author | ||
| 260 | |c 2019 | ||
| 520 | |a The crude methanol extract of Sphenocentrum jollyanum root exhibited 98% and 80% antimicrobial activity against Aspergillus fumigatus Pinh and Vancomycin resistant enterococcus (VRE) at a concentration of 200 μg/mL, with ICso 11.45 and 12.95 μg/mL, respectively. The ethyl acetate fraction of methanol extract showed in-vitro antimicrobial activity against A. fumigatus Pinh at 83% with ICso of <8 μg/mL. The phytochemical investigation of ethyl acetate fraction yielded six compounds, which were identified by their NMR, IR and MS spectral analyses as two new phytoecdysteroidal glycosides Sphenocentroside A (1), and NUSART Sphenocentroside B (2), and four known phytoecdysteroids: polypodoaurein (3), polypodine B (4), ecdysterone (5), and 20, 26-dihydroxyecdysone (6). | ||
| 024 | 8 | |a 0039-128X | |
| 024 | 8 | |a 1878-5867 | |
| 024 | 8 | |a ui_art_ajayi_two_2019 | |
| 024 | 8 | |a Steroids | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12134 | |
| 653 | |a Sphenocentrum jollyanum | ||
| 653 | |a Phytoecdysteroids | ||
| 653 | |a Antimicrobial activity | ||
| 653 | |a Aspergillus fumigatus | ||
| 653 | |a Vancomycin resistant enterococcus | ||
| 245 | 0 | 0 | |a Two New phytoecdysteroids from sphenocentrum jollyanum pierre root |