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Peritoneal dialysis in childhood acute kidney injury: experience in Southwest Nigeria
Background: The choices for renal replacement therapy (RRT) in childhood acute kidney injury (AKI) are lim¬ited in low-resource settings. Peritoneal dialysis (PD) appears to be the most practical modality for RRT in young children with AKI in such settings. Data from sub-Saharan Africa on the use of...
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2012
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12173 | ||
| 042 | |a dc | ||
| 720 | |a Ademola, A. D. |e author | ||
| 720 | |a Asinobi, A. O. |e author | ||
| 720 | |a Ogunkunle, O. O. |e author | ||
| 720 | |a Yusuf, B. N. |e author | ||
| 720 | |a Ojo, O. E. |e author | ||
| 260 | |c 2012 | ||
| 520 | |a Background: The choices for renal replacement therapy (RRT) in childhood acute kidney injury (AKI) are lim¬ited in low-resource settings. Peritoneal dialysis (PD) appears to be the most practical modality for RRT in young children with AKI in such settings. Data from sub-Saharan Africa on the use of PD in childhood AKI are few. Methods: We performed a retrospective study of chil¬dren who underwent PD for AKI at a tertiary-care hospital in southwest Nigeria from February 2004 to March 2011 (85 months). Results: The study included 27 children (55.6% female). Mean age was 3.1 ± 2.6years, with the youngest being 7 days, and the oldest, 9 years. The causes of AKI were in¬travascular hemolysis (n = 11), septicemia (n = 8), acute glomerulonephritis (n = 3), gastroenteritis (n = 3), and hemolytic uremic syndrome (n = 2). Peritoneal dialysis was performed manually using percutaneous or adapted catheters. Duration of PD ranged from 6 hours to 12 days (mean: 5.0 ± 3.3 days). The main complications were peri¬tonitis (n = 10), pericatheter leakage (n = 9), and catheter outflow obstruction (n = 5). Of the 27 patients, 19 (70%) survived till discharge. Conclusions: In low-resource settings, PD can be suc¬cessfully performed for the management of childhood AKI. In our hospital, the use of adapted catheters may have contributed to the high complication rates. Peritoneal di¬alysis should be promoted for the management of childhood AKI in low-resource settings, and access to percutaneous or Tenckhoff catheters, dialysis fluid, and automated PD should be increased. | ||
| 024 | 8 | |a 0896-8608 | |
| 024 | 8 | |a ui_art_ademola_peritoneal_2015 | |
| 024 | 8 | |a Peritoneal Dialysis International 32(3), pp. 267-272 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12173 | |
| 653 | |a Children | ||
| 653 | |a acute kidney injury | ||
| 653 | |a low-resource setting | ||
| 653 | |a peritoneal dialysis catheters | ||
| 653 | |a outcome | ||
| 653 | |a survival | ||
| 653 | |a Nigeria | ||
| 245 | 0 | 0 | |a Peritoneal dialysis in childhood acute kidney injury: experience in Southwest Nigeria |