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Predictors and outcome of acute kidney injury after non-cardiac paediatric surgery
Background: It is necessary to define the problem of acute kidney injury (AKI) after non-cardiac surgery in order to design interventions to prevent AKI. The study aimed to evaluate the occurrence, determinants and outcome of AKI among children undergoing general (non-cardiac) surgery. Methods: This...
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2019
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12218 | ||
| 042 | |a dc | ||
| 720 | |a Lawal, T. A. |e author | ||
| 720 | |a Raji, Y. R. |e author | ||
| 720 | |a Ajayi, S. O. |e author | ||
| 720 | |a Ademola, A. D. |e author | ||
| 720 | |a Ademola, A. F. |e author | ||
| 720 | |a Ayandipo, O. O. |e author | ||
| 720 | |a Adigun, T. |e author | ||
| 720 | |a Ogundoyin, O. O. |e author | ||
| 720 | |a Olulana, D. I. |e author | ||
| 720 | |a Asinobi, A. O. |e author | ||
| 720 | |a Salako, B. L. |e author | ||
| 260 | |c 2019 | ||
| 520 | |a Background: It is necessary to define the problem of acute kidney injury (AKI) after non-cardiac surgery in order to design interventions to prevent AKI. The study aimed to evaluate the occurrence, determinants and outcome of AKI among children undergoing general (non-cardiac) surgery. Methods: This was a prospective cohort study of patients aged ≤ 15 years who had general surgery over 18 months period at a tertiary hospital in Nigeria. AKI was evaluated at 6 and 24 h and within 7 days of surgery. Data were analysed using SPSS version 21. Results: A total of 93 patients were studied with age ranging from 3 days to 15 years (median = 4 years). AKI occurred within 24 h of surgery in 32 (34.4%) and cumulatively over 7 days in 33 (35.5%). Patients who had sepsis were nearly four times as likely as others to develop perioperative AKI (OR = 3.52, 95% CI 1.21, 10.20, p = 0.021). Crude mortality rate was 12.1% (4/33); no mortality was recorded among those without AKI, p = 0.014. Conclusion: Perioperative AKI occurred in 35.5% of children who underwent general (non-cardiac) surgery. Patients who had sepsis were four times more likely than others to develop AKI. Mortality was documented only in patients who had AKI. | ||
| 024 | 8 | |a 2059-1381 | |
| 024 | 8 | |a ui_art_lawal_predictors_2019 | |
| 024 | 8 | |a Renal Replacement Therapy 5 (15) | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12218 | |
| 653 | |a Acute kidney injury | ||
| 653 | |a Paediatric | ||
| 653 | |a Perioperative | ||
| 653 | |a Non-cardiac surgery | ||
| 245 | 0 | 0 | |a Predictors and outcome of acute kidney injury after non-cardiac paediatric surgery |