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Susceptibility patterns of common bacteria and fungal species isolated from sexually transmitted diseased patients to xylopia aethiopica (annonaceae)

The hexane and methanolic extracts of the leaves, stem, stem bark, and root bark of Xylopia aethiopica were investigated for their anti-microbial activities against some common bacteria and fungal strains isolated from sexually transmitted diseased patients and some standard organisms. The hexane an...

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Published: 2003-09
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/12275
042 |a dc 
720 |a Oluremi, B. B.  |e author 
720 |a Adeniyi, B. A.  |e author 
260 |c 2003-09 
520 |a The hexane and methanolic extracts of the leaves, stem, stem bark, and root bark of Xylopia aethiopica were investigated for their anti-microbial activities against some common bacteria and fungal strains isolated from sexually transmitted diseased patients and some standard organisms. The hexane and methanol crude extracts showed varying degrees of anti-microbial activities at varying concentrations while the stem bark exhibited significant broad-spectrum anti-microbial activity. The methanolic extract of the stem bark showed better activity than hexane, was fractionated and the four fractions collected were tested for their antimicrobial activity against the organisms implicated in STD at a concentration of 10mg/ml. The results suggest that the active fractions A and B contain constituents which can be isolated, characterized and identified for effective management of both bacterial and fungal STD’s. Preliminary Phytochemical screening revealed the presence of alkaloids. sugars, cardiac glycoside and saponins and the absence of anthraquinones and tannins. 
024 8 |a 0189-8434 
024 8 |a ui_art_oluremi_susceptibility_2003 
024 8 |a Nigerian Journal of Pharmaceutical Research 2, pp. 48-53 
024 8 |a https://repository.ui.edu.ng/handle/123456789/12275 
653 |a Xylopia aethiopica 
653 |a Antimicrobial activity 
653 |a Sexually transmitted diseased patients 
245 0 0 |a Susceptibility patterns of common bacteria and fungal species isolated from sexually transmitted diseased patients to xylopia aethiopica (annonaceae)