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Anti-inflammatory and antimicrobial activities of hippocratea indica root bark and poga oleosa fruits
The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantl...
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| Format: | Article |
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2007
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12277 | ||
| 042 | |a dc | ||
| 720 | |a Ogbole, O. O. |e author | ||
| 720 | |a Ekor, M. N. |e author | ||
| 720 | |a Oluremi, B. B. |e author | ||
| 720 | |a Ajaiyeoba, E. O. |e author | ||
| 720 | |a Gbolade, A. A. |e author | ||
| 720 | |a Ayoola, M. A. |e author | ||
| 720 | |a Adeyemi, A. A. |e author | ||
| 260 | |c 2007 | ||
| 520 | |a The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants. | ||
| 024 | 8 | |a 0189-6016 | |
| 024 | 8 | |a ui_art_ogbole_anti-inflammatory_2007 | |
| 024 | 8 | |a African Journal of Traditional, Complementary and Alternative Medicines 4(3), pp. 372-376 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12277 | |
| 653 | |a Hippocratea indica | ||
| 653 | |a Poga oleosa | ||
| 653 | |a Anti-inflammatory | ||
| 653 | |a Antimicrobial | ||
| 245 | 0 | 0 | |a Anti-inflammatory and antimicrobial activities of hippocratea indica root bark and poga oleosa fruits |