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Comparative assessment of antibacterial activity of uvaria chamae parts

Methanolic extracts of the root, stem and leaf of Uvaria chamae were evaluated for their antibacterial activity against Methicillin-Resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Escherichia coli, Klebsiella spp, Proteus spp, and typed strains E. coli ATCC 25922, S. aureus ATCC 25923...

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Published: 2010
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/12291
042 |a dc 
720 |a Oluremi, B. B.  |e author 
720 |a Osungunna, M. O.  |e author 
720 |a Omafuma, O. O.  |e author 
260 |c 2010 
520 |a Methanolic extracts of the root, stem and leaf of Uvaria chamae were evaluated for their antibacterial activity against Methicillin-Resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Escherichia coli, Klebsiella spp, Proteus spp, and typed strains E. coli ATCC 25922, S. aureus ATCC 25923 and Pseudomonas aeruginosa ATCC27853 using standard agar diffusion method at 50, 100, 150, 200 and 250 mg/ml. Preliminary phytochemical screening revealed the presence of alkaloids, tannins, flavonoids, cardiac glycosides and cyanogenic glycosides. In general, the stem bark extract inhibited the growth of all the tested organisms with leaf extract showing the least antibacterial activity. The MIC of methanolic stem extract on E. coli, MRSA, Klebsiella spp, Proteus spp, E. coli ATCC 25922, S. aureus ATCC 25923 and P. aeruginosa ATCC 27853 were 5.62, 12.59, 200, 35.48, 28.18, 5.62 and 19.95 mg/ml respectively while that of root extract with the exclusion of Klebsiella spp were 31.62, 10.0, 3.55 2.82, 12.59 and 39.81 mg/ml respectively. Methanolic leaf extract was found to have MIC 200, 19.95, 250, 250, 250 and 200 mg/ml respectively with no MIC value against P. aeruginosa. 
024 8 |a 1996-0808 
024 8 |a ui_art_oluremi_comparative_2010 
024 8 |a African Journal of Microbiology Research 4(13), pp. 1391-1394 
024 8 |a https://repository.ui.edu.ng/handle/123456789/12291 
653 |a Methicillin-resistant 
653 |a Phytochemical screening 
653 |a Alkaloids 
653 |a Cyanogenic 
653 |a Flavonoids 
245 0 0 |a Comparative assessment of antibacterial activity of uvaria chamae parts