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Factors associated with treatment success among pulmonary tuberculosis and HIV co-infected patients in Oyo State, South West-Nigeria

BACKGROUND The co-existence of Tuberculosis (TB) and Human immunodeficiency Virus (HIV) is known to increase morbidity and mortality in patients. The determinants of treatment success in TB- HIV co-infection are not yet well studied. Such information can help optimise treatment and reduce morbidity...

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Published: 2013
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/12425
042 |a dc 
720 |a Oladimeji, O. O.  |e author 
720 |a Obasanya, J. O.  |e author 
720 |a Daniel, O. J.  |e author 
720 |a Gidado, M.  |e author 
720 |a Akolo, C.  |e author 
720 |a Oladimeji, K. E.  |e author 
720 |a Atilola, O.  |e author 
720 |a Ajayi, T.  |e author 
720 |a Adeyinka, A. D.  |e author 
720 |a Osman, E.  |e author 
720 |a Odusote, T.  |e author 
720 |a Awe, A.  |e author 
720 |a Lawalu, O.  |e author 
720 |a Omoniyi, A.  |e author 
720 |a Dairo, D. M.  |e author 
720 |a Adedokun, B. O.  |e author 
720 |a Adeoye, I. A.  |e author 
720 |a Igodekwe, F. C.  |e author 
720 |a Hassan, A.  |e author 
720 |a Onoja, M. A.  |e author 
260 |c 2013 
520 |a BACKGROUND The co-existence of Tuberculosis (TB) and Human immunodeficiency Virus (HIV) is known to increase morbidity and mortality in patients. The determinants of treatment success in TB- HIV co-infection are not yet well studied. Such information can help optimise treatment and reduce morbidity and mortality. OBJECTIVE To determine factors associated with anti- tubercular treatment success among TB /HIV coinfected patients. METHODS A cross sectional study was carried out in fifty three DOT clinics and treatment centres using tuberculosis patient’s records from January 2009 to December 2010 in Oyo state, Nigeria. The study population consisted of 7905 tuberculosis patients. Information on variables of interest were obtained with the use of data extraction forms. Chi-square and logistic regression were used to test the relationship between TB/ HIV co- infection and socio-demographic variables, clinical characteristics and treatment success. RESULTS Prevalence of TB /HIV co-infection was found to be 14.2%. Patients with TB-HIV co-infection were younger and more likely to be females. There were statistically significant association between treatment success and gender, marital status and patient point of care. After adjusting for other variables, it was found that patients receiving treatment in private facilities were independently less likely to be successfully treated compared with those receiving care in Public facilities. Female patients were also independently more likely to have better treatment outcome than male. CONCLUSION In addition to patients’ point of care, gender of the patients can adversely impact on their treatment success. Efforts from the government to strengthening the private public mix, health education and media awareness on adherence to treatment to improve treatment success should be intensified in the country. 
024 8 |a 2992-345X 
024 8 |a The Nigerian Health Journal 13(2), pp. 75-81. 
024 8 |a ui_art_oladimeji_factors_2013 
024 8 |a https://repository.ui.edu.ng/handle/123456789/12425 
653 |a Tuberculosis 
653 |a Human immunodeficiency virus 
653 |a Directly observe therapy short-course 
653 |a Treatment success 
653 |a Co- infection. 
245 0 0 |a Factors associated with treatment success among pulmonary tuberculosis and HIV co-infected patients in Oyo State, South West-Nigeria