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Seroprevalence rates of hepatitis c virus (hcv) antibody and hepatitis b virus surface antigen (hbsag) in blood donors in a southwestern nigerian city

Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the pres...

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Published: 2014
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/12430
042 |a dc 
720 |a Motayoa, B. O.  |e author 
720 |a Akpa, O. M.  |e author 
720 |a Ezeani, I.  |e author 
720 |a Faneye, A. O.  |e author 
720 |a Udo, U. A.  |e author 
720 |a Onoja, B.  |e author 
260 |c 2014 
520 |a Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the presence of Hepatitis B virus surface antigen (HBsAg) and HCV using a rapid immunochromatographic kit (DiaSpot®). Demographic information was also collected. Males constituted 96.4%, singles were the majority with 65%. Prevalence of HBsAg was 9.8%, HCV 1.3%, and dual positivity 0.3%. Prevalence of HBsAg and HCV among males was 10.2% and 1.4%, while females recorded 0.0% for HCV and HBsAg. Dual positivity was recorded in a male (0.33%). Analysis of the study variables revealed that only educational status was statistically associated with positivity of HBsAg (χ2 = 7.49, p = 0.02), HCV prevalence was highest in the illiterate group it was not statistically significant (P > 0.05). We report the prevalence rates of anti-HCV Ab and HBsAg in blood donors from Ogun State, Nigeria. Our results reveals higher rate of HBsAg and evidence of co-infection with both viruses, illiteracy was the only variable associated with HBV infection. We advocate for the inclusion of anti-HBc or HBeAg in donor screening in our environment. 
024 8 |a 1532-4230 
024 8 |a ui_art_motayo_seroprevalence_2014 
024 8 |a Journal of Immunoassay and Immunochemistry 36(1), pp.91-99 
024 8 |a https://repository.ui.edu.ng/handle/123456789/12430 
653 |a HBsAg 
653 |a HCV 
653 |a seoprevailence 
653 |a blood donors 
653 |a abeokuta 
245 0 0 |a Seroprevalence rates of hepatitis c virus (hcv) antibody and hepatitis b virus surface antigen (hbsag) in blood donors in a southwestern nigerian city