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HBV Infection among HIV-infected cohort And HIV-negative Hospital attendees in South Western Nigeria
"Background: Prevalence, association and probable mode of acquisition of HBV and HIV dual infections have not been fully explored. Thus, HBV intervention plan and services are sometimes exclusively targeted towards HIV-infected population. We investigated HBV infection among HIV-infected cohort in c...
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2014
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12535 | ||
| 042 | |a dc | ||
| 720 | |a Adewumi, M. O. |e author | ||
| 720 | |a Donbraye, E. |e author | ||
| 720 | |a Odaibo, G. N. |e author | ||
| 720 | |a Bakarey, A. S. |e author | ||
| 720 | |a Opaleye, O. O. |e author | ||
| 720 | |a Olaleye, D. O. |e author | ||
| 260 | |c 2014 | ||
| 520 | |a "Background: Prevalence, association and probable mode of acquisition of HBV and HIV dual infections have not been fully explored. Thus, HBV intervention plan and services are sometimes exclusively targeted towards HIV-infected population. We investigated HBV infection among HIV-infected cohort in comparison with HIV-negative hospital attendees to ascertain dual infectivity pattern; thereby encouraging appropriat allotment of intervention services. A total of 349 (M=141; F=208; Mean=33.98 years; Range= 0.33-80 years) plasma specimens from two virus diagnostic laboratories in south-western Nigeria were analysed. These include 182 HIV-positive and 167 HIV-negative specimens from ART and GDV laboratories respectively. The specimens were initially screened for detectable HIV antigen/antibody, and subsequently HBsAg by ELISA technique. Overall, HBsAg was detected in 20.92% (95% CI: 16.65-25.19%) of the patients. Also, 24.82% (95% CI: 17.69 31.95%) and 18.27% (95% CI: 13.02-23.52%) HBsAg positivity was recorded for males and females respectively. CHI square analysis showed no association (P=0.14) between gender and prevalence of HBsAg. Similarly, comparison of prevalence of HBsAg by age groups shows no significant difference (P=0.24). Overall, no significant difference (P=0.59) was observed in the prevalence of HBsAg among the HIV-infected cohort and HIV-negative hospital attendees. Results of the study confirm endemicity and comparable rates of HBV infection independent of HIV-status. | ||
| 024 | 8 | |a 2006-0165 | |
| 024 | 8 | |a 2504-1018 | |
| 024 | 8 | |a ui_art_adewumi_HBV_2014 | |
| 024 | 8 | |a African Journal of Infectious Diseases 9(1), pp.14–17 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12535 | |
| 653 | |a ART | ||
| 653 | |a HBV | ||
| 653 | |a HIV | ||
| 653 | |a Nigeria | ||
| 653 | |a Dual positivity | ||
| 245 | 0 | 0 | |a HBV Infection among HIV-infected cohort And HIV-negative Hospital attendees in South Western Nigeria |