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Persistence in treatment for one year among patients in Nigeria with first-episode of Schizophrenia
Objective: The aim of this study was to examine the magnitude of poor persistence in treatment among patients with schizophrenia and to identify associated factors. Methods: All eligible patients (N5216) seen at the University College Hospital in Ibadan, Nigeria, over a five-year period were retros...
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| Format: | Article |
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2014
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12558 | ||
| 042 | |a dc | ||
| 720 | |a Esan, O.B. |e author | ||
| 260 | |c 2014 | ||
| 520 | |a Objective: The aim of this study was to examine the magnitude of poor persistence in treatment among patients with schizophrenia and to identify associated factors. Methods: All eligible patients (N5216) seen at the University College Hospital in Ibadan, Nigeria, over a five-year period were retrospectively followed up until the time of their last visit. Time to first default was examined by Kaplan-Meier survival analyses. Alog-rank test was used to compare survival times for different variables. The contribution of the variables that affected time to default was examined by Cox regression analysis. Results: Only 24% of the sample remained in treatment at the one-year follow-up. Persistence as measured by mean6SE time to all-cause treatment default was 17.8061 .44 weeks. Of several variables examined, including whether patients were taking first- or second-generation antipsychotics, none were found to predict persistence. Conclusions: Persistence in treatment of patients with a first episode of schizophrenia was low. | ||
| 024 | 8 | |a 1075-2730 | |
| 024 | 8 | |a 1557-9701 | |
| 024 | 8 | |a ui_art_esan_persistence_2014 | |
| 024 | 8 | |a Psychiatric Services, 65(9), pp. 1174-1176 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12558 | |
| 653 | |a Schizophrenia | ||
| 653 | |a First-episode | ||
| 653 | |a Nigeria | ||
| 245 | 0 | 0 | |a Persistence in treatment for one year among patients in Nigeria with first-episode of Schizophrenia |