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Combining depot antipsychotic with an assertive monitoring programme for treating first-episode schizophrenia in a resource- constrained setting
Aim: To assess the feasibility and effectiveness of depot antipsychotic (flupentixol decanoate) combined with an assertive monitoring programme (AMP) in first-episode schizophrenia. Methods: This was a prospective, non-comparative, longitudinal study conducted over 12 months assessing patient accep...
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| Format: | Article |
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2016
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12569 | ||
| 042 | |a dc | ||
| 720 | |a Chiliza, B. |e author | ||
| 720 | |a Ojagbemi, A. |e author | ||
| 720 | |a Esan, O.B. |e author | ||
| 720 | |a Asmal, L. |e author | ||
| 720 | |a Oosthuizen, P. |e author | ||
| 720 | |a Kidd, M. |e author | ||
| 720 | |a Gureje, O. |e author | ||
| 720 | |a Emsley, R. |e author | ||
| 260 | |c 2016 | ||
| 520 | |a Aim: To assess the feasibility and effectiveness of depot antipsychotic (flupentixol decanoate) combined with an assertive monitoring programme (AMP) in first-episode schizophrenia. Methods: This was a prospective, non-comparative, longitudinal study conducted over 12 months assessing patient acceptance, adherence, outcome in domains of psychopathology, functionality and quality of life, and tolerability. Results: Of 207 participants, 149 (72%) completed 12 months of treatment. Acceptance of and adherence to depot was good. Treatment response was achieved by 170 (82%) participants and remission by 124 (60%). Thirty-three (19%) responders relapsed and10(5%) participants met a priori criteria for treatment resistance. Treatment was generally well tolerated. Conclusions: Combination of depot antipsychotic with an AMP maybe an effective and safe intervention linearly phase of schizophrenia, and may be particularly suitable for resource constrained settings. | ||
| 024 | 8 | |a 1751-7885 | |
| 024 | 8 | |a 1751-7893 | |
| 024 | 8 | |a ui_art_chiliza_combining_2016 | |
| 024 | 8 | |a Early Intervention in Psychiatry 10(1), pp. 54-62 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12569 | |
| 653 | |a Antipsychotic | ||
| 653 | |a Developing country | ||
| 653 | |a Psychotic disorder | ||
| 653 | |a Schizophrenia. | ||
| 245 | 0 | 0 | |a Combining depot antipsychotic with an assertive monitoring programme for treating first-episode schizophrenia in a resource- constrained setting |