Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Rubella antibody avidity among rubella seropositive women attending a tertiary care facility in Nigeria
Objectives: The aim of this study was to determine the seroprevalence of rubella virus antibodies among women of reproductive age group and assess risk factors of rubella infection. Materials and Methods: A cross-sectional study was carried out among 285 women aged between 15 and 49 years. Enzyme-li...
Saved in:
| Format: | Article |
|---|---|
| Published: |
2015
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000njm a2000000a 4500 | ||
|---|---|---|---|
| 001 | oai:repository.ui.edu.ng:123456789/12708 | ||
| 042 | |a dc | ||
| 720 | |a Suleiman, S. T. |e author | ||
| 720 | |a Bakare, R. |e author | ||
| 720 | |a Akanbi II, A. A. |e author | ||
| 720 | |a Fowotade, A. |e author | ||
| 720 | |a Billiaminu, S. A. |e author | ||
| 720 | |a Durowade, K. A. |e author | ||
| 260 | |c 2015 | ||
| 520 | |a Objectives: The aim of this study was to determine the seroprevalence of rubella virus antibodies among women of reproductive age group and assess risk factors of rubella infection. Materials and Methods: A cross-sectional study was carried out among 285 women aged between 15 and 49 years. Enzyme-linked immunosorbent assay (ELISA) method was used to detect and quantify human immunoglobulin G (IgG) antibodies with avidity for rubella virus in sera of participants. Socio-demographic characteristics of the participants, along with recent and previous history of fever and rash among others were obtained using a questionnaire. Statistical analysis was carried out using SPSS version 16. Results: Seroprevalence of rubella IgG among women of reproductive age in Ilorin was 92.3% (95% CI: 89.2%-95.4%). Thus susceptibility rate to rubella infection was 7.7%. Majority (87.1%) of the IgG seropositive participants had high rubella IgG avidity, implying past rubella infection or reinfections. Seroprevalence was significantly higher among participants from lower educational and socio-economic classes compared with other participants (P = .035 and P = .023, respectively). There was a negative correlation between age and rubella specific IgG titer (P = .000). Thus rubella specific IgG titer decreases with increasing age. Conclusion: There is need for vaccination of susceptible women of reproductive age in Ilorin as the rubella susceptibility rate was higher than the 5.0% target set by the World Health Organization (WHO) for prevention of congenital rubella syndrome (CRS). | ||
| 024 | 8 | |a 2330- 4456 | |
| 024 | 8 | |a ui_art_suleiman_rubella_2015 | |
| 024 | 8 | |a International Journal of Women’s Health and Reproduction Sciences 3(30), pp. 136–141 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12708 | |
| 653 | |a Antibody avidity | ||
| 653 | |a Nigeria | ||
| 653 | |a Rubella | ||
| 653 | |a Seroepidemiologic studies | ||
| 245 | 0 | 0 | |a Rubella antibody avidity among rubella seropositive women attending a tertiary care facility in Nigeria |