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Serosurvey of human T cell lymphotropic virus I/II among blood donors in Gombe (Nigeria)
Aim: This study was carried out to determine the prevalence of human T cell lymphotropic virus I/II (HTLV I/II) among blood donors at the Federal Teaching Hospital Gombe (FTHG), North-eastern, Nigeria. Methods: A total of 355 blood donors were recruited at the hematology department of FTHG for a hos...
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2016
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/12712 | ||
| 042 | |a dc | ||
| 720 | |a Manga, M. M. |e author | ||
| 720 | |a Fowotade, A. |e author | ||
| 720 | |a Yuguda, S. |e author | ||
| 720 | |a Iya, G. A. |e author | ||
| 720 | |a Yahaya, M. |e author | ||
| 720 | |a Sheriff, Y. M. |e author | ||
| 720 | |a Omoruyi, E. C. |e author | ||
| 720 | |a Yola, I. M. |e author | ||
| 720 | |a Bakare, R. A. |e author | ||
| 260 | |c 2016 | ||
| 520 | |a Aim: This study was carried out to determine the prevalence of human T cell lymphotropic virus I/II (HTLV I/II) among blood donors at the Federal Teaching Hospital Gombe (FTHG), North-eastern, Nigeria. Methods: A total of 355 blood donors were recruited at the hematology department of FTHG for a hospital based crosssectional study and were screened/confirmed for HTLV I/II by ELISA and western blot methods. Results: Seroprevalence of HTLV I/II among the 355 participants with mean age of 30.77 years (±8.27) was 6.5% on screening with ELISA but confirmed to be 0% by western blot. Majority were males, 352 (99.2%) and mostly (45.9%) between 21–30 years of age. Donors for family replacements predominated (85.1%) with more than half (58.6%) being first time blood donors. Conclusion: This study reveals the absence of HTLV I/II among blood donors in Gombe Northeastern Nigeria. It also highlights the possibility of false positivity in some of the reported prevalence of HTLV I and II from some parts of Nigeria that were based on screening tests only. The importance of confirmatory testing in all research works on HTLV (including HTLV 3 and HTLV 4) is further strengthened with this study. There is however the need for a larger study and the use of molecular diagnostics to reconfirm this assertion. | ||
| 024 | 8 | |a 2230-9020 | |
| 024 | 8 | |a ui_art_manga_serosurvey_2016 | |
| 024 | 8 | |a International Journal of Blood transfusion and Immunohematology 6, pp. 12–19 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/12712 | |
| 653 | |a Blood donors | ||
| 653 | |a Gombe | ||
| 653 | |a Human T cell lymphotropic virus I/II (HTLV I/II) | ||
| 653 | |a Nigeria | ||
| 653 | |a T cell | ||
| 245 | 0 | 0 | |a Serosurvey of human T cell lymphotropic virus I/II among blood donors in Gombe (Nigeria) |