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Characterization of hepatitis delta virus strains spreading in Abuja, Nigeria

Hepatitis delta virus (HDV) is responsible for the most severe form of liver disease in humans. So far, eight genotypes (HDV‐1 to ‐8) have been individualized worldwide. Little is known about HDV strains that spread in Nigeria. HDV genotyping was performed in 15 anti–HDV positive samples from a coho...

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Published: 2019
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/12810
042 |a dc 
720 |a Ifeorah, I. M.  |e author 
720 |a Faleye, T. O. C.  |e author 
720 |a Bakarey, A. S.  |e author 
720 |a Adewumi, O. M.  |e author 
720 |a Gerber, A.  |e author 
720 |a Le Gal, F.  |e author 
720 |a Adeniji, J. A  |e author 
720 |a Gordien, E.  |e author 
720 |a Onyemelukwe, N. F.  |e author 
260 |c 2019 
520 |a Hepatitis delta virus (HDV) is responsible for the most severe form of liver disease in humans. So far, eight genotypes (HDV‐1 to ‐8) have been individualized worldwide. Little is known about HDV strains that spread in Nigeria. HDV genotyping was performed in 15 anti–HDV positive samples from a cohort of 306 hepatitis B virus (HBV)‐infected patients in Abuja (Nigeria). Phylogenetic analyses revealed 90% were HDV‐1, two among them clustering with European/Asian HDV‐1, the remaining one being HDV‐6. It was also found that two members of a couple superinfected with the same HDV strain, were enveloped by two different HBV strains of genotype E. 
024 8 |a 0146-6615 
024 8 |a 1096-9071 
024 8 |a ui_art_ifeorah_characterization_2019 
024 8 |a Journal of Medical Virology 91(9), pp,1688–1692 
024 8 |a https://repository.ui.edu.ng/handle/123456789/12810 
653 |a Blood 
653 |a Epidemiology 
653 |a Hepatitis B Virus 
653 |a Hepatitis D Virus 
653 |a Satellite 
653 |a Subviral Agents 
653 |a Virus Classification 
245 0 0 |a Characterization of hepatitis delta virus strains spreading in Abuja, Nigeria