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A Bayesian sensitivity analysis of the effect of different random effects distributions on growth curve models

Growth curve data consist of repeated measurements of a contin uous growth process of human, animal, plant, microbial or bacterial genetic data over time in a population of individuals. A classical approach for analyzing such data is the use of non-linear mixed effects models under normality assumpt...

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Published: 2020
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/13095
042 |a dc 
720 |a Ganjali, M.  |e author 
720 |a Baghfalaki, T.  |e author 
720 |a Fagbamigbe, A. F.  |e author 
260 |c 2020 
520 |a Growth curve data consist of repeated measurements of a contin uous growth process of human, animal, plant, microbial or bacterial genetic data over time in a population of individuals. A classical approach for analyzing such data is the use of non-linear mixed effects models under normality assumption for the responses. But, sometimes the underlying population that the sample is extracted from is an abnormal population or includes some homogeneous sub-samples. So, detection of original properties of the population is an important scientific question of interest. In this paper, a sensitivity analysis of using different parametric and non-parametric distributions for the random effects on the results of applying non-linear mixed models is proposed for emphasizing the possible heterogeneity in the population. A Bayesian MCMC procedure is developed for parameter estimation and inference is performed via a hierarchical Bayesian framework. The methodology is illustrated using a real data set on study of influence of menarche on changes in body fat accretion. 
024 8 |a 2316-090X 
024 8 |a ui_art_ganjali_bayesian_2020 
024 8 |a Afrika Statistika 15(3), pp. 2387–2393 
024 8 |a https://repository.ui.edu.ng/handle/123456789/13095 
653 |a Bayesian paradigm 
653 |a Dirichlet process 
653 |a growth curve models 
653 |a mixed effects model 
653 |a repeated measurements data 
653 |a sensitivity analysis 
245 0 0 |a A Bayesian sensitivity analysis of the effect of different random effects distributions on growth curve models