Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
The gelling properties of Dillenia indica mucilage in benzyl benzoate emulgel formulations
The objective of the study was to evaluate the gelling properties of Dillenia indica mucilage in benzyl benzoate emulgel formulation. Mucilage was extracted from the fruits of Dillenia indica using established methods and characterized by rheology and swelling. Emulsion (F1) was prepared using the c...
Saved in:
| Format: | Article |
|---|---|
| Published: |
2020
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000njm a2000000a 4500 | ||
|---|---|---|---|
| 001 | oai:repository.ui.edu.ng:123456789/13334 | ||
| 042 | |a dc | ||
| 720 | |a Ajala, T. O. |e author | ||
| 720 | |a Eraga, S. |e author | ||
| 720 | |a Akin-Ajani, O. D |e author | ||
| 260 | |c 2020 | ||
| 520 | |a The objective of the study was to evaluate the gelling properties of Dillenia indica mucilage in benzyl benzoate emulgel formulation. Mucilage was extracted from the fruits of Dillenia indica using established methods and characterized by rheology and swelling. Emulsion (F1) was prepared using the continental emulsification method. Gelling agents (2 %w /v) were prepared by dispersing in distilled water with constant stirring at a moderate speed usinga magnetic stirrer. F1 was added to the gel (0-75 %w /w) to obtain emulgel formulations and evaluated using viscosity, globule size, pH, release profiles and kinetic modeling. Data were expressed as mean ± SD, and similarity factor (f2) was used to compare all formulations. Formulation viscosity was significantly higher with carbopol than with Dillenia; globule sizes increased with concentration of gelling agents, and pH reduced as the concentration of Dillenia increased. All formulations showed controlled release properties with t80 ranging between 114 and 660 min. The release was governed by Korsmeyer-Peppas model. Formulation F5 prepared with 50 % Dillenia showed highest similarity to F4 prepared with 75 %w /w carbopol. Dillenia indica demonstrated acceptable gelling properties comparable with that of carbopol and could be improved for use in emulgel formulations. | ||
| 024 | 8 | |a 2175-9790 | |
| 024 | 8 | |a ui_art_ajala_gelling_2020 | |
| 024 | 8 | |a Brazilian Journal of Pharmaceutical Sciences 58. pp.1-15 | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/13334 | |
| 653 | |a Dillenia indica mucilage | ||
| 653 | |a Benzyl benzoate | ||
| 653 | |a Emulsion | ||
| 653 | |a Gelling agents | ||
| 653 | |a Emulgel | ||
| 653 | |a formulations. | ||
| 245 | 0 | 0 | |a The gelling properties of Dillenia indica mucilage in benzyl benzoate emulgel formulations |