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Sudden death in giant pituitary adenomas: two case reports with literature review

Pituitary macroadenomas are rare tumors constituting <1% of intracranial tumors. The giant macroadenomas are even rarer and have the potential to cause fatality due mostly to mass effects within the intracranial space. Most cases are nonfunctional and are either null cell adenomas or gonadotroph ade...

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Published: 2017
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/13453
042 |a dc 
720 |a Salami, A.  |e author 
720 |a Babatunde, T.  |e author 
720 |a Ogun, O.  |e author 
720 |a Lawan, A.  |e author 
720 |a Abubakar‑Akanbi, S.  |e author 
720 |a Nweke, M.  |e author 
260 |c 2017 
520 |a Pituitary macroadenomas are rare tumors constituting <1% of intracranial tumors. The giant macroadenomas are even rarer and have the potential to cause fatality due mostly to mass effects within the intracranial space. Most cases are nonfunctional and are either null cell adenomas or gonadotroph adenomas in which symptoms may have been ignored by the patient. Sudden deaths from intracranial tumors are uncommon and pituitary adenomas are very rarely associated with unexpected deaths. Here, we present two cases of giant pituitary adenomas both of which were undiagnosed before demise of the patient. The autopsy report showed no other findings except the sellar tumor. Immunohistochemistry of both tumors showed null cell adenoma 
024 8 |a 2635-3938 
024 8 |a ui_art_salami_sudden_2017 
024 8 |a Annals of Tropical Pathology 8(1), pp. 47-50 
024 8 |a https://repository.ui.edu.ng/handle/123456789/13453 
653 |a Giant adenoma 
653 |a null cell 
653 |a pituitary 
245 0 0 |a Sudden death in giant pituitary adenomas: two case reports with literature review