Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Antimicrobial use and detection of cefotaxime-resistant Enterobacteriaceae in thè pig production chain, Ogun State, Nigeria
Cefotaxime belongs to thè third-generation cephalosporin group of antimicro- bials, which are classified as criticai for thè treatment of infections in humans. The upsurge in thè incidence of cefotaxime-resistant (C-R) bacteria from animai sources is of global public health importance. This study in...
Saved in:
| Format: | Article |
|---|---|
| Published: |
2020
|
| Tags: |
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000njm a2000000a 4500 | ||
|---|---|---|---|
| 001 | oai:repository.ui.edu.ng:123456789/13533 | ||
| 042 | |a dc | ||
| 720 | |a Ojo, O. E. |e author | ||
| 720 | |a Akinyemi, M. I. |e author | ||
| 720 | |a Amosun, E. A. |e author | ||
| 720 | |a Hassan, J. O. |e author | ||
| 720 | |a Dipeolu, M. A. |e author | ||
| 260 | |c 2020 | ||
| 520 | |a Cefotaxime belongs to thè third-generation cephalosporin group of antimicro- bials, which are classified as criticai for thè treatment of infections in humans. The upsurge in thè incidence of cefotaxime-resistant (C-R) bacteria from animai sources is of global public health importance. This study investigated thè pres- ence of C-R Enterobacteriaceae in thè pig production chain in Ogun State, Nigeria, and examined C-R isolates for production of extended-spectrum P-lactamase (ESBL). The knowledge, attitude and practices of pig farmers regarding antimicrobial usage were also investigated. C-R bacteria were detected in 54 (17.8%) out of 303 samples. C-R isolates were identified as Escherichia coli (n = 22), Klebsiella spp. (n = 17), Enterobacter aerogenes (n = 10) and Citrobacter freundii (n = 5). The organisms were present in feces from on-farm pigs (15/109; 13.7%), fresh pork at slaughterhouses (19/40; 47.5%), frozen pork at retail shops (7/28; 25.0%), cutting surfaces of butchers' tools (7/52; 13.5%), and abattoir effluent water (6/41; 14.6%). No C-R bacteria were detected in ready-to-eat pork. Three isolates of Es. coli and one of K. pneumoniae were ESBL-producers and pos- sessed WaCTX_M_15 ESBL gene variant. ESBL-producing Es. coli belonged to phylo- genetic group A. All C-R isolates were resistant to more than three antimicrobi- als from different classes of antimicrobials. Tetracycline, ampicillin, amoxicillin, ciprofloxacin and enrofloxacin were among thè commonly used antimicrobials in pig production, whereas cephalosporins were rarely used. Farmers knew that pigs could serve as reservoirs of pathogenic bacteria transmissible to humans. However, they were not aware that thè use of antimicrobials in pig production could lead to thè development and proliferation of antimicrobial-resistant bacteria in pigs. Efforts should be made to improve awareness among farmers on thè roles of antimicrobial use in thè emergence and dissemination of antimicrobial- resistant bacteria in animai production. | ||
| 024 | 8 | |a 1951-6711 | |
| 024 | 8 | |a ui_art_ojo_antimicrobial_2019 | |
| 024 | 8 | |a Revue d’elevage et de medicine veterinaire des pays tropicaux. 72(4) pp. 1-8. | |
| 024 | 8 | |a https://repository.ui.edu.ng/handle/123456789/13533 | |
| 245 | 0 | 0 | |a Antimicrobial use and detection of cefotaxime-resistant Enterobacteriaceae in thè pig production chain, Ogun State, Nigeria |