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Spinal Schwannomatosis Unassociated with Phakomatosis: A Case Report

Schwannomas are slow-growing, encapsulated benign tumors of the peripheral nerves. The multiplicity of these tumors has been linked with genetic anomalies associated with neurofibromatosis. Schwannomatosis is a rare autosomal-dominant tumor syndrome characterized by the occurrence of multiple schwan...

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Published: 2021
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/13711
042 |a dc 
720 |a Badejo, O. A.  |e author 
720 |a Nwafuluaku, E. C.  |e author 
720 |a Salami, A. A.  |e author 
260 |c 2021 
520 |a Schwannomas are slow-growing, encapsulated benign tumors of the peripheral nerves. The multiplicity of these tumors has been linked with genetic anomalies associated with neurofibromatosis. Schwannomatosis is a rare autosomal-dominant tumor syndrome characterized by the occurrence of multiple schwannomas of the peripheral nervous system, with no involvement of the vestibular nerve. This contrasts with neurofibromatosis 2, in which the existence of bilateral vestibular schwannomas is pathognomonic. Spinal schwannomatosis without features of neurofibromatosis is a very rare occurrence, previously unreported in Nigerian neurosurgical literature. We present a Nigerian patient with cervical intradural-extramedullary and thoracic intramedullary spinal schwannomas. His treatment outcome and a brief literature review were also discussed. 
024 8 |a 2811-1826 
024 8 |a ui_art_badejo_spinal_2021 
024 8 |a Archives of Neurosurgery in africa 2(2), pp. 29-34 
024 8 |a https://repository.ui.edu.ng/handle/123456789/13711 
653 |a Schwannomas 
653 |a Congenital neurilemmomatosis 
653 |a Intradural tumors 
653 |a Neurofibromatosis type 
245 0 0 |a Spinal Schwannomatosis Unassociated with Phakomatosis: A Case Report