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Use of intermittent preventive therapy and incidence of acute malaria in pregnancy among postpartum women at University College Hospital, Ibadan, Nigeria

Background: Malaria in pregnancy remains a significant cause of feto‑maternal morbidity and mortality especially in regions of high prevalence like Nigeria. Intermittent preventive therapy (IPT) for malaria is an important measure to abate this menace. Aim: The aim is to determine the uptake and eff...

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Published: 2021
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/13757
042 |a dc 
720 |a Ifebude, J. E.  |e author 
720 |a Idowu, C. O.  |e author 
720 |a Awolude, O. A.  |e author 
260 |c 2021 
520 |a Background: Malaria in pregnancy remains a significant cause of feto‑maternal morbidity and mortality especially in regions of high prevalence like Nigeria. Intermittent preventive therapy (IPT) for malaria is an important measure to abate this menace. Aim: The aim is to determine the uptake and effectiveness of IPT in relation to the occurrence of malaria, despite the use of IPT in pregnancy. Patients, Materials and Methods: This was a cross‑sectional study conducted in UCH, Ibadan from October 1, to December 31, 2020. A total of 150 postpartum women were selected using the total sampling technique of all consenting participants. Structured questionnaires were used for data collection. Results: About 87.7% of the respondents took IPT in the index pregnancy. Of these, 15.4%, 50.8%, and 33.8% of participants took one, two, and three doses, respectively. The factors that determined intermittent preventive treatment for malaria in pregnancy (IPTp) uptake include occupation (P = 0.001), booking status (P = 0.002), antenatal care attendance (P = 0.001), and level of IPTp awareness (P = 0.002). About 48.0% of respondents indicated that they were treated for malaria in the index pregnancy. Meanwhile, only about 15.3% of those who took IPT were treated for malaria in pregnancy. It was found that the use of IPT (P = 0.03) and an increasing number of IPT doses used (P = 0.03) were associated with a reduction in the prevalence of malaria in pregnancy. Conclusion: The uptake of the current recommendation for IPT‑SP that stipulates the use of monthly doses of IPT till delivery with a target of a minimum of three doses was quite poor. There is therefore an urgent need for widespread awareness and implementation of the World Health Organization and national guidelines on prevention of malaria. The prevalence of malaria declined with the number of doses of IPT‑SP used by the respondents. This emphasizes the need for adequate dosing of IPT. 
024 8 |a 1115-2613 
024 8 |a 2667-0526 
024 8 |a ui_art_ifebude_use_2021 
024 8 |a Nigerian Journal of Medicine 30(6), pp. 701-708 
024 8 |a https://repository.ui.edu.ng/handle/123456789/13757 
653 |a Intermittent preventive treatment for malaria in pregnancy 
653 |a malaria in pregnancy 
653 |a postpartum women 
653 |a sulfadoxine‑pyrimethamine 
245 0 0 |a Use of intermittent preventive therapy and incidence of acute malaria in pregnancy among postpartum women at University College Hospital, Ibadan, Nigeria