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Prevalence of HIV-I subtypes in infected concordant and discordant couples in Nigera
The peptide binding immunoassay (PELISA) was used as previously described to determine HIV-I subtypes among 60 married HIV-I sero-positive individuals and their spouses identified at the University College Hospital, Ibadan in order to investigate the rate of heterosexual partners by different HIV-I...
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| Format: | Article |
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2001-08
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/2235 | ||
| 042 | |a dc | ||
| 720 | |a Odaibo, G. N. |e author | ||
| 720 | |a Olaleye, O. D. |e author | ||
| 720 | |a Ruppach, H. |e author | ||
| 720 | |a Fasanmade, A. A. |e author | ||
| 720 | |a Olubuyide, S. O. |e author | ||
| 720 | |a Dietrich, U. |e author | ||
| 260 | |c 2001-08 | ||
| 520 | |a The peptide binding immunoassay (PELISA) was used as previously described to determine HIV-I subtypes among 60 married HIV-I sero-positive individuals and their spouses identified at the University College Hospital, Ibadan in order to investigate the rate of heterosexual partners by different HIV-I subtypes in Nigeria. Out of the 60 couples whose blood samples were analyzed, 33 (55%) were both positive HIV while only one spouse of the couples was sero-positive among the other 27. Using the McNemer test for discordant paired samples, an insignificant (P=0.0636) differnce was obtained between male to female and female to male transmission. Subtypes A, B, C and E were dtected among these individuals. Most (82.3%) of the subtypes C and all of the subtype E(12) were detected among the tranmitters (couples with concordant sero-positive status). This study indicates that HIV-I subtypes C and E may be more efficiently transmitted heterosexually than the other subtypes. | ||
| 024 | 8 | |a Bioscience Research Communications 13(4), pp. 459-464 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/2235 | |
| 653 | |a HIV-l sublypcs; | ||
| 653 | |a HIV-1 predmee; | ||
| 653 | |a Concordan[ coupla; | ||
| 653 | |a DMmi mples; | ||
| 653 | |a Nigeria | ||
| 245 | 0 | 0 | |a Prevalence of HIV-I subtypes in infected concordant and discordant couples in Nigera |