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Helicobacter pylori serology and evaluation of gastroduodenal disease in Nigerias with dyspepsia
Helicobacter pylori (H. pylori) has been strongly associated with various gastroduodenal diseases worldwide with only a few studies emanating from developing countries. The objectives of this study were to determine the prevalence of serum immunoglobulin G (lgG) and underlying gastroduodenal pathol...
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2004
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/2302 | ||
| 042 | |a dc | ||
| 720 | |a Otegbayo, J. A. |e author | ||
| 720 | |a Oluwasola, O. A. |e author | ||
| 720 | |a Yakubu, A. |e author | ||
| 720 | |a Odaibo, G. N. |e author | ||
| 720 | |a Olaleye, O. D. |e author | ||
| 260 | |c 2004 | ||
| 520 | |a Helicobacter pylori (H. pylori) has been strongly associated with various gastroduodenal diseases worldwide with only a few studies emanating from developing countries. The objectives of this study were to determine the prevalence of serum immunoglobulin G (lgG) and underlying gastroduodenal pathology in Nigerian patients with dyspepsia and ascertain the usefulness of H.pylori lgG screening in decreasing endoscopic workload in dyspeptics in Nigeria. fifty-five patients with dyspepsia and 55 age and sex-matched apparently normal control were screened for H.pylori lgG using ImmunocombrII kits. Each of the 55 patients were also examined endoscopically with biopsies taken appropriately. Serology was positive in 94.5% and 92.7% of dyspeptic patients and controls respectivley. Gastroduodenal inflammation was the commonest endoscopic finding, 43 (78.18%). Other findings were malignant gastric tumour 6(10.9%), reflux oesophagitis 3(5.45%), gastric ulcer 2(3.64%), and duodenal ulcer in 1(1.82%). chronic gastritis was the main histopathologic finding in the dyspeptic patients. It is concluded that serum H. pylori lgG cannot be used as a screening procedure to reduce endoscopic workload in Nigerian patients with dyspepsia. | ||
| 024 | 8 | |a African Journal of Clinical and Experimental Microbiology 5(1), pp. 131-138 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/2302 | |
| 653 | |a dyspepsia; | ||
| 653 | |a Helicobacterpylori serology; | ||
| 653 | |a gastroduodenal disease | ||
| 245 | 0 | 0 | |a Helicobacter pylori serology and evaluation of gastroduodenal disease in Nigerias with dyspepsia |