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A review of the effect of 5-fluorouracil on the outcome of trabeculectomy in Ibadan
Aim: To retrospectively assess the outcome of trabeculectomy performed using an intraoperative sponge soaked in 5-fluorouracil (50 mg/ml). Methods: Trabeculectomy with an intraoperative sponge soaked with 5-f1uorouracil (5-FU) was performed in 21 eyes of 14 patients. The reduction in intraocular pre...
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| Format: | Article |
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2004-06
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/2592 | ||
| 042 | |a dc | ||
| 720 | |a Baiyeroju, A. M |e author | ||
| 720 | |a Ubah, J.N |e author | ||
| 260 | |c 2004-06 | ||
| 520 | |a Aim: To retrospectively assess the outcome of trabeculectomy performed using an intraoperative sponge soaked in 5-fluorouracil (50 mg/ml). Methods: Trabeculectomy with an intraoperative sponge soaked with 5-f1uorouracil (5-FU) was performed in 21 eyes of 14 patients. The reduction in intraocular pressure (lOP), complications and variations in visual acuity were noted. Results: The mean preoperative lOP was 31.5 ± 10.6 mmHg. The mean postoperative lOP was 7.3 ± 5.7mmHg on the second postoperative day and 17.5 ± 9.8mmHg at 3 months. Postoperative complications were mostly transient, with 33% of eyes requiring postoperative antiglaucoma therapy to reduce lOP. Visual acuity Improved postoperatively in 3 eyes, worsened in 9 eyes and remained the same in 9 eyes. Conclusion: Even though a small study, an intraoperative sponge soaked with 5-FU seems to be a safe and effective adjunct to trabeculectomy. | ||
| 024 | 8 | |a 0189-9171 | |
| 024 | 8 | |a Nigerian Journal of Ophthalmology 12(1), pp. 14-18 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/2592 | |
| 653 | |a 5-f1uorouracil, | ||
| 653 | |a trabeculectomy, | ||
| 653 | |a gl, | ||
| 653 | |a Hlcomc1, | ||
| 653 | |a Nigerian | ||
| 245 | 0 | 0 | |a A review of the effect of 5-fluorouracil on the outcome of trabeculectomy in Ibadan |