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Mycobacterium tuberculosis and mycobacterium africanum in stools from children attending an immunization clinic in Ibadan, Nigeria
"BACKGROUND:Tuberculosis is a major cause of childhood morbidity and mortality in Nigeria. Diagnosis of childhood tuberculosis is a global challenge making early treatment a mirage. In this study we investigated the stools of children for the presence of mycobacteria. METHODS:Stool samples from chil...
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2009
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/2607 | ||
| 042 | |a dc | ||
| 720 | |a Cadmus, S. I. B. |e author | ||
| 720 | |a Jenkins, A. O. |e author | ||
| 720 | |a Godfroid, J. |e author | ||
| 720 | |a Osinusi, K. |e author | ||
| 720 | |a Adewole, I. F. |e author | ||
| 720 | |a Murphy, R. L. |e author | ||
| 720 | |a Taiwo, B. O. |e author | ||
| 260 | |c 2009 | ||
| 520 | |a "BACKGROUND:Tuberculosis is a major cause of childhood morbidity and mortality in Nigeria. Diagnosis of childhood tuberculosis is a global challenge making early treatment a mirage. In this study we investigated the stools of children for the presence of mycobacteria. METHODS:Stool samples from children aged 3 days to 3 years who presented for postnatal immunization at a large university-based clinic in Nigeria, were subjected to Ziehl-Neelsen staining. Samples with acid-fast bacilli were further processed using mycobacterial culture, spoligotyping, and deletion typing. RESULTS:One hundred and ninety-two stool samples from different children were collected and processed. Thirty (15.6%) had acid-fast bacilli. Of these, eight had Mycobacterium tuberculosis and one had Mycobacterium africanum. CONCLUSIONS:Approximately 5% (9/192) of apparently well children had evidence of potentially serious tuberculosis infection. The usefulness of stool specimens for diagnosing pediatric tuberculosis warrants further investigation." | ||
| 024 | 8 | |a International Journal of Infectious Diseases, pp. 1-5 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/2607 | |
| 245 | 0 | 0 | |a Mycobacterium tuberculosis and mycobacterium africanum in stools from children attending an immunization clinic in Ibadan, Nigeria |