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THE REACTIONS OF SOME ACTIVATED AROMATIC HALIDES WITH PIPERIDINS, AND N-BUTYLANINE IN DIPOLAR APROTIC AND DIPOLAR PROTIC SOLVENTS
The reactions of 2-chloro-5-nitro pyridine with piperidine have been studied in acetone and in nethanol. In acetone, the rate constants are measured as a function of the anine concentration. In methanol, the Arrhenius parameters are obtained. In methanol, except for a very slight (almost negligible)...
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| Format: | Thesis |
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1975
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/4683 | ||
| 042 | |a dc | ||
| 720 | |a ADENLE, M. A. |e author | ||
| 260 | |c 1975 | ||
| 520 | |a The reactions of 2-chloro-5-nitro pyridine with piperidine have been studied in acetone and in nethanol. In acetone, the rate constants are measured as a function of the anine concentration. In methanol, the Arrhenius parameters are obtained. In methanol, except for a very slight (almost negligible) downward trend of rate constants at very high concentration which is explained in terms of Charge - transfer complexes, there is no base catalysis and the observed rate constants are the rates of formation of the intermediate complex. The rates of reaction of 1-X-2, 4-dinitrobenzene (X=F, Cl) with piperidine and n-butylamine in methanol, acetone, and chloroform (stabilised and destabilised) have been measured as a function of the amine concentration. In acetone, the reactions of both substrates with piperidine show true base catalysis with K3/K2 > 50 in both cases. In Chloroform with n-butylamine, there is very little rate increase with increasing amine concentration. For both Substrates, K3/K2=3. This is explained in terms of hydrogen-bonding in the intermediate state. In methanol, the reaction of the chloro Substrate with piperidine gives a small linear increase of rate constants with increasing amine concentration; while for the fluoro substrate, the graph of rate constants against amine concentration gives a doubly sloped curve. This is due to some special unknown medium effects. In acetone, the reactions with n-butylamine give rather peculiar results. The chloro substrate appears to be more sensitive to catalysis by amine than the fluoro substrate - a Situation hitherto unknown. In general, for the reactions in methanol and Chloroform, there is not much base influence; while those in acetone are dependent on the base strength. | ||
| 024 | 8 | |a ui_thesis_adenle_m.a._reactions_1975 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/4683 | |
| 245 | 0 | 0 | |a THE REACTIONS OF SOME ACTIVATED AROMATIC HALIDES WITH PIPERIDINS, AND N-BUTYLANINE IN DIPOLAR APROTIC AND DIPOLAR PROTIC SOLVENTS |