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Effect of aqueous extract of spondias mombin on the spermiogram of wistar rats

Twenty-five male rats were divided into four groups (A-E) and treated for twenty-one days with aqueous leaf extract of Spondias mombin which is a fruit tree whose leaf extract is commonly consumed as local remedies in traditional medicine practice. Graded dosages of the extracts were assigned to the...

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Published: 2011
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/5389
042 |a dc 
720 |a Oloye, A. A.  |e author 
720 |a Oyeyemi, M. O.  |e author 
720 |a Ola-Davies, O. E.  |e author 
720 |a Innamah, O. A.  |e author 
260 |c 2011 
520 |a Twenty-five male rats were divided into four groups (A-E) and treated for twenty-one days with aqueous leaf extract of Spondias mombin which is a fruit tree whose leaf extract is commonly consumed as local remedies in traditional medicine practice. Graded dosages of the extracts were assigned to the groups as follows: 200mg/kg, 400 mg/kg, 600 mg/kg and 800 mg/kg for groups B, C, D and E, respectively. Group A rats which serve as control were given distilled water. Thereafter, spermiogram (mass activity, progress motility, live-dead and morphology) was evaluated. Rats treated with aqueous extracts of spondias mombin at 600 mg/kg body weight has the highest (p<0.05) spermatozoa concentration of 40.51x106 cells/ml. compared with other groups A, B, C and E which had 21.48 x 106, 29.58 x 106, 35.81 x 106/ml, respectively. At dosage of 800 mg/kg highest (p<0.05) sperm motility of 70 ± 4.81% was observed. Compared with other groups A, B, C and D which had 65.0 ± 0.00, 65.5 ± 6.71 and 68.0 ± 2.89%, respectively. The percentage average livability of the control group and of those given 200 mg/kg BW, 70 ± 23.45 and 70 ± 23.09, respectively, were lower than those from group C (77.5 ± 15.55), D (87.5 ± 17.68) and E (80.0 ± 17.32) with group D having the highest average percentage livability. Coiled tail was the predominant abnormality in group A, B and E consisting 40.3%, 24.3% and 30.0% of the total abnormalities, respectively. The work recommended aqueous extract of spondias mombin at concentration of 600mg/ml for of fertility enhancement in male animals. 
024 8 |a 0378-9721 
024 8 |a ui_art_oloye_effect_2011 
024 8 |a Bulletin of Animal Health and Production in Africa 59, pp. 95-99 
024 8 |a http://ir.library.ui.edu.ng/handle/123456789/5389 
653 |a Effect 
653 |a Aqueous 
653 |a Extract 
653 |a Spondias mombin 
653 |a Spermiogram 
653 |a Wistar rats 
245 0 0 |a Effect of aqueous extract of spondias mombin on the spermiogram of wistar rats