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Testicular and epididymal parameters of spondias mombin L. (anacardiaceae) protected male wistar rats exposed to sodium arsenite
The testicular and epididymal protective potential of Spondias mombin. L in arsenic-treated rats was carried out. Thirty-five male albino rats (225-228g) were used and grouped into 7 (A to G), each group containing 5 rats. Group A was treated with 0.1ml Dimethysulphoxide (DMSO), B (0.1ml of Distille...
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2014
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| LEADER | 00000njm a2000000a 4500 | ||
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| 001 | oai:repository.ui.edu.ng:123456789/5398 | ||
| 042 | |a dc | ||
| 720 | |a Ola-Davies, O. |e author | ||
| 720 | |a Ajani, O. S. |e author | ||
| 720 | |a Oyeyemi, M. O. |e author | ||
| 720 | |a Ekundayo, S. |e author | ||
| 260 | |c 2014 | ||
| 520 | |a The testicular and epididymal protective potential of Spondias mombin. L in arsenic-treated rats was carried out. Thirty-five male albino rats (225-228g) were used and grouped into 7 (A to G), each group containing 5 rats. Group A was treated with 0.1ml Dimethysulphoxide (DMSO), B (0.1ml of Distilled water), C (Sodium arsenite; SA-2.5mg/kg body weight), D (Ethylacetate fraction), E (Ethylacetate fraction for 7 days and Sodium arsenite the 7th day), F (Methanolic fraction for 7days and Sodium arsenite the 7th day) and G (Methanolic fraction for 7 days). The results showed significant decrease (P>0.05) in the mean value of both the right and left testes length for group C (treated with Sodium arsenite only) compared to the remaining groups. It was also observed that Group G (treated with Methanolic fraction) had the lowest mean value (P>0.05) for the left and right testes weight and the left and right testicular diameter when compared to other groups. It was also observed that Group G (treated with Methanolic fraction) had the lowest mean values for all the epididymal parameters in this study. There was a significant decrease in the mean value of left epididymal weight, right and left epididymal length of group G compared to group B (treated with distilled water) and group A (treated with DMSO). It was concluded that the Methanolic fraction of Spondias mombin. L has no protective effect on the male albino rats exposed to sodium arsenite as it caused a reduction in epididymal parameters and testicular weight and diameter which may trigger testicular degeneration leading to infertility. | ||
| 024 | 8 | |a 1992-6197 | |
| 024 | 8 | |a ui_art_ola-davies_testicular_2014 | |
| 024 | 8 | |a Global Veterinaria 12(2), pp. 232-236 | |
| 024 | 8 | |a http://ir.library.ui.edu.ng/handle/123456789/5398 | |
| 653 | |a Spondias mombin | ||
| 653 | |a Wistar Rats | ||
| 653 | |a Testicular Parameters | ||
| 653 | |a Epididymal Parameters | ||
| 245 | 0 | 0 | |a Testicular and epididymal parameters of spondias mombin L. (anacardiaceae) protected male wistar rats exposed to sodium arsenite |