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Maternal and neonatal outcomes of pre-eclampsia in African black women, South West Nigeria

Aim: To evaluate the biophysical, biochemical and clinical characteristics of pre-eclamptic pregnancies as a suitable approach to access and manage pregnancy at risk of pre-eclampsia. Methods: 89 pregnant women with preeclampsia were investigated longitudinally at prepartum and postpartum. The bioph...

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Published: 2015-10
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/8267
042 |a dc 
720 |a Adeosun, O. G.  |e author 
720 |a Charles-Davies, M. A.  |e author 
720 |a Ogundahunsi, O. A.  |e author 
720 |a Ogunlewe, J.  |e author 
260 |c 2015-10 
520 |a Aim: To evaluate the biophysical, biochemical and clinical characteristics of pre-eclamptic pregnancies as a suitable approach to access and manage pregnancy at risk of pre-eclampsia. Methods: 89 pregnant women with preeclampsia were investigated longitudinally at prepartum and postpartum. The biophysical, biochemical and clinical variables of both mother and neonate of pre-eclamptic pregnancy obtained by standard procedures were compared with the normotensive pregnant controls. Results: Mean gestational ages were significantly lower in pre-eclampsia than in control group (P < 0.001). Caesarean section operations were significantly higher in the group with pre-eclamptic pregnancy compared with the control group (P < 0.05). Pre-eclamptic group recorded significantly higher maternal and neonatal mortality rates than the normotensive controls (P < 0.05). The mean placenta weight, one and five minutes apgar score of neonates of preeclamptic pregnancy were significantly lower compared with the controls (P<0.05). Systolic and diastolic blood pressures at each of the study periods in pre-eclamptic group were significantly elevated compared with the nomortensive pregnancy (P< 0.001). Pre-eclamptic pregnancies had varying degrees of significant microalbuminuria compared with the controls (P < 0.001). Conclusion: Low birth weight, high maternal and neonatal mortality rates, and Cesarean section, low gestational age, apgar scores, placenta weight, elevated blood pressures and microalbuminuria occur more frequently in pre-eclampsia than in healthy normotensive pregnancy. 
024 8 |a 2276-7797 
024 8 |a ui_art_adeosun_maternal_2015 
024 8 |a Greener Journal of Medical Sciences 5(4), pp. 67-76 
024 8 |a http://ir.library.ui.edu.ng/handle/123456789/8267 
653 |a Biophysical 
653 |a Biochemical 
653 |a Clinical 
653 |a Micro-albuminuria 
653 |a Neonate 
653 |a Pre-eclampsia 
653 |a Normotensive 
245 0 0 |a Maternal and neonatal outcomes of pre-eclampsia in African black women, South West Nigeria