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Cost-effectiveness analysis of mectizan treatment programme for onchocerciasis control: operational experiences in two district of Southern Nigeria

Objectives: This study analyze the operational costs of two Mectizan treatment strategies in relation to their effectiveness. Methods: The study was conducted in 24 communities located in Irewole and Egbeda districts of Osun and Oyo State, Nigeria respectively. Cost-effectiveness analysis included r...

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Published: 2009
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/8458
042 |a dc 
720 |a Osungbade, K. O.  |e author 
720 |a Olumide, E. A. A.  |e author 
720 |a Lawanson, A. O.  |e author 
720 |a Asuzu, M. C.  |e author 
260 |c 2009 
520 |a Objectives: This study analyze the operational costs of two Mectizan treatment strategies in relation to their effectiveness. Methods: The study was conducted in 24 communities located in Irewole and Egbeda districts of Osun and Oyo State, Nigeria respectively. Cost-effectiveness analysis included retrospective analysis of cost of treatment, review of records of distributors, estimation of overall cost-effectiveness ratio of treatment and distribution, calculation of mean cost-effectiveness ratios and statistical comparison of the mean cost-effectiveness ratios. Results: Overall cost of treatment per person through mobile distribution was N27.39 (USD1.16) while the corresponding overall cost through community-directed distribution was N14.35 (USD0.61). Overall cost of distribution per tablet through mobile distribution was N20.97 (USD0.89) while the corresponding overall cost through community-directed distribution was N8.39 (USD0.36). The difference between the mean cost-effectiveness ratios for treatments through mobile distribution, 56.79, and community directed distribution, 32,53, was not statistically significant (p=0.120265). Similarly, the difference between the mean cost-effectiveness ratios for distribution of tablets through mobile distribution, 40.83, and community-directed distribution, 19.17, was not statistically significant (p=0.167249). Treatment coverages were 59% and 80%, and 2,376 and 4,148 tablets were respectlveIy distributed, Conclusion: Distribution of Mectizan tablets by community-directed distributors was more cost-effective than by mobile health staff, but the differences in cost ere not statistically significant. However, this could ensure self-reIiance and sustainability of treatment programmes, which are prerequisites for decision making on treatment strategies. 
024 8 |a 1595-8272 
024 8 |a ui_art_osungbade_cost-effectiveness_2009 
024 8 |a Nigerian Journal of Health and Biomedical Sciences 8(1), pp. 8-15 
024 8 |a http://ir.library.ui.edu.ng/handle/123456789/8458 
653 |a Onchocerciasis 
653 |a Treatment 
653 |a Cost-effectiveness 
653 |a Mectizan 
653 |a Distribution 
245 0 0 |a Cost-effectiveness analysis of mectizan treatment programme for onchocerciasis control: operational experiences in two district of Southern Nigeria