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Pharyngo-cutaneous fistula post total-laryngectomy: a local experience

Background: Pharyngo-cutaneous fistula is a major complication of total laryngectomy. Despite its significant impact on the patients' nutrition and management outcome, there is lack of consensus for recognising high-risk patients and factors associated with fistula formation. Hence, this study was a...

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Published: 2020-03
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/9246
042 |a dc 
720 |a Ogunkeyede, S. A.  |e author 
720 |a Adeyemo, A. A.  |e author 
720 |a Daniel, A.  |e author 
720 |a Yaro, P. J.  |e author 
720 |a Ogundoyin, O. A  |e author 
260 |c 2020-03 
520 |a Background: Pharyngo-cutaneous fistula is a major complication of total laryngectomy. Despite its significant impact on the patients' nutrition and management outcome, there is lack of consensus for recognising high-risk patients and factors associated with fistula formation. Hence, this study was aimed at determining the incidence of pharyngo-cutaneous fistula and factors associated with fistula formation. Methods: A retrospective collection of data on all cases of laryngeal cancer diagnosed histologically and had total laryngectomy, in the Otorhinolaryngology Department of a tertiary centre in Southwestern, Nigeria, from 2007 – 2016. The data collected include age, gender, tumour stage, tracheostomy, adjuvant therapy extent of laryngectomy procedure and factors for pharyngocutaneous fistula. Results: Forty-two patients had total laryngectomy, male to female ratio was 7.4:1 and mean age was 52.3 ± 2.1 years. All patients had pathological diagnosis of stage 3 (83.3%) and stage 4 (16.7%) laryngeal cancer, respectively. The incidence of pharyngo-cutaneous fistula was11.9% and the factors related to fistula formation were prior radiotherapy treatment and diabetes. Age, gender, neck dissection procedures, site of primary tumor and emergency tracheostomy did not contribute to fistula formation. Spontaneous fistula closure was achieved in all cases except one patient who had surgical closure. Conclusion: Pharyngo-cutaneous fistula formation post-surgery is related to the presence of co-morbidities. The high percentage of spontaneous closure underscores the need for a conservative management approach 
024 8 |a 1115-2613 
024 8 |a ui_art_ogunkeyede_pharyngocutaneous_2020 
024 8 |a Nigerian Journal of Medicine 29(1) January - March 2020. Pp. 69 - 72 
024 8 |a http://ir.library.ui.edu.ng/handle/123456789/9246 
653 |a Laryngeal cancer 
653 |a Laryngectomy 
653 |a Neck dissection 
653 |a Pharyngo-cutaneous fistula 
653 |a Post-surgery 
653 |a Radiotherapy 
245 0 0 |a Pharyngo-cutaneous fistula post total-laryngectomy: a local experience