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Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola

Dissertation (MSc (Genetics))--University of Pretoria, 2017.

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Other Authors: Slippers, Bernard
Format: Thesis
Language:English
Published: 2026
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access_status_str Open Access
author2 Slippers, Bernard
author_browse Slippers, Bernard
author_facet Slippers, Bernard
collection Thesis
description Dissertation (MSc (Genetics))--University of Pretoria, 2017.
format Thesis
id oai:repository.up.ac.za:2263/110192
institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:37:37.270Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2026
publishDateRange 2026
publishDateSort 2026
record_format dspace
source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/110192 Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola Slippers, Bernard u1205245@tuks.co.za Reva, Oleg Pierneef, Rian Smidt, Alisa Postma Clasen, Frederick Johannes Horizontal gene transfer eukaryotes eukaryotic evolution endosymbiosis tree of life genomic islands Dissertation (MSc (Genetics))--University of Pretoria, 2017. Horizontal gene transfer (HGT), the movement of genetic material between different species, is a well recognized mechanism for rapid evolution and adaptation in prokaryotes. It was not until fairly recent that the existence of HGT in eukaryotes have also been appreciated to such an extend that it is recognized as a fundamental evolutionary driving force for adaptation. Here we review the most recent work that explored the horizontal transmission of genetic material in eukaryotes. Firstly, different biological and computational limitations that currently constrain HGT research in eukaryotes are highlighted. Secondly, several examples of HGT in eukaryotes are discussed to emphasize its potential on the evolution of complex organisms. The importance of endosymbiosis is accentuated by using it as a model system for the evolutionary importance and underlying mechanisms of HGT. Other examples of where HGT allowed species to adapt to new ecological niches, expand their metabolic capabilities and adopt entire new lifestyles are then used to sketch the influence of HGT on specific eukaryotic species. Thirdly, the potential impact that HGT may have on our perception of the tree of life is discussed using different examples of HGT in all domains of life. Lastly, genes that are frequently transferred between organisms are summarized with specific reference to genomic islands that can potentially act as “genomic vehicles” of HGT in eukaryotes, similar to its role in prokaryotes. Genetics MSc (Genetics) 2026-05-15T17:26:37Z 2026-05-15T17:26:37Z 18/02/14 2017 Dissertation http://hdl.handle.net/2263/110192 en application/pdf
spellingShingle Horizontal gene transfer
eukaryotes
eukaryotic evolution
endosymbiosis
tree of life
genomic islands
Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title_full Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title_fullStr Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title_full_unstemmed Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title_short Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola
title_sort horizontal gene transfer in eukaryotes with special focus on the nematode deladenus siricidicola
topic Horizontal gene transfer
eukaryotes
eukaryotic evolution
endosymbiosis
tree of life
genomic islands
url http://hdl.handle.net/2263/110192