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Dissertation (MSc (Genetics))--University of Pretoria, 2017.
| Other Authors: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2026
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| _version_ | 1867613530850590720 |
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| access_status_str | Open Access |
| author2 | Slippers, Bernard |
| author_browse | Slippers, Bernard |
| author_facet | Slippers, Bernard |
| collection | Thesis |
| description | Dissertation (MSc (Genetics))--University of Pretoria, 2017. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/110192 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:37:37.270Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/110192 Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola Slippers, Bernard u1205245@tuks.co.za Reva, Oleg Pierneef, Rian Smidt, Alisa Postma Clasen, Frederick Johannes Horizontal gene transfer eukaryotes eukaryotic evolution endosymbiosis tree of life genomic islands Dissertation (MSc (Genetics))--University of Pretoria, 2017. Horizontal gene transfer (HGT), the movement of genetic material between different species, is a well recognized mechanism for rapid evolution and adaptation in prokaryotes. It was not until fairly recent that the existence of HGT in eukaryotes have also been appreciated to such an extend that it is recognized as a fundamental evolutionary driving force for adaptation. Here we review the most recent work that explored the horizontal transmission of genetic material in eukaryotes. Firstly, different biological and computational limitations that currently constrain HGT research in eukaryotes are highlighted. Secondly, several examples of HGT in eukaryotes are discussed to emphasize its potential on the evolution of complex organisms. The importance of endosymbiosis is accentuated by using it as a model system for the evolutionary importance and underlying mechanisms of HGT. Other examples of where HGT allowed species to adapt to new ecological niches, expand their metabolic capabilities and adopt entire new lifestyles are then used to sketch the influence of HGT on specific eukaryotic species. Thirdly, the potential impact that HGT may have on our perception of the tree of life is discussed using different examples of HGT in all domains of life. Lastly, genes that are frequently transferred between organisms are summarized with specific reference to genomic islands that can potentially act as “genomic vehicles” of HGT in eukaryotes, similar to its role in prokaryotes. Genetics MSc (Genetics) 2026-05-15T17:26:37Z 2026-05-15T17:26:37Z 18/02/14 2017 Dissertation http://hdl.handle.net/2263/110192 en application/pdf |
| spellingShingle | Horizontal gene transfer eukaryotes eukaryotic evolution endosymbiosis tree of life genomic islands Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title | Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title_full | Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title_fullStr | Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title_full_unstemmed | Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title_short | Horizontal gene transfer in eukaryotes, with special focus on the nematode Deladenus siricidicola |
| title_sort | horizontal gene transfer in eukaryotes with special focus on the nematode deladenus siricidicola |
| topic | Horizontal gene transfer eukaryotes eukaryotic evolution endosymbiosis tree of life genomic islands |
| url | http://hdl.handle.net/2263/110192 |