Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Serum lactate in canine babesiosis
Dissertation (MMed Vet (Med))--University of Pretoria, 2004.
Saved in:
| Other Authors: | |
|---|---|
| Format: | Thesis |
| Published: |
University of Pretoria
2013
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613633959165953 |
|---|---|
| access_status_str | Open Access |
| author2 | Lobetti, R.G. (Remo Giuseppe) |
| author_browse | Lobetti, R.G. (Remo Giuseppe) |
| author_facet | Lobetti, R.G. (Remo Giuseppe) |
| collection | Thesis |
| dc_rights_str_mv | © 2005, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MMed Vet (Med))--University of Pretoria, 2004. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/22944 |
| institution | University of Pretoria (South Africa) |
| last_indexed | 2026-06-10T12:39:15.557Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/22944 Serum lactate in canine babesiosis Lobetti, R.G. (Remo Giuseppe) mirinda.nel@up.ac.za Nel, Mirinda No keywords available UCTD Dissertation (MMed Vet (Med))--University of Pretoria, 2004. Canine babesiosis typically causes a haemolytic anemia and results in hypoxia and sepsis, which can eventually result in multiple organ dysfunction. Human patients with severe injury or disease such as shock, sepsis and malaria often have persistent hyperlactataemia, and there is a correlation between blood lactate and survival rate. There are various similarities between human malaria and canine babesiosis, eg. anaemia, renal failure, cerebral forms, coagulopathy, hepatopathy, pulmonary oedema, and shock. In severe malaria, lactate levels in blood rise in direct proportion to the severity of the disease. Venous lactate concentrations measured at 4 hours after admission appears to be the best prognostic indicator in severe malaria. In dogs blood lactate has been shown to be of prognostic value in patients with gastric dilatationvolvulus and in dogs admitted to intensive care units. Blood lactate has also been shown to be of prognostic value in equine colic. Blood lactate was determined in ninety dogs with naturally occurring canine babesiosis. Forty-five dogs (50%) presented with hyperlactataemia (blood lactate > 2.5mmol/L) and 20 (22.2%) with hypoglycaemia (blood glucose < 3.3 mmol/L). Measurements significantly associated with mortality were hypoglycaemia on admission, blood lactate > 5mmol/L on admission, blood lactate > 2.5 mmol/L at 8, 16 and 24 hours after admission, and increase or < 50% decrease in blood lactate within 8 and 16 hours after admission. Blood lactate persistently > 4.4 mmol/L indicated a very poor prognosis. The study concluded that serial blood lactate measurements are useful in predicting survival in dogs with severe and complicated canine babesiosis. Companion Animal Clinical Studies unrestricted 2013-09-06T14:02:46Z 2005-03-03 2013-09-06T14:02:46Z 2005-02-17 2006-03-03 2005-03-03 Dissertation Nel, M 2005, Serum lactate in canine babesiosis, MMed dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/22944 > http://hdl.handle.net/2263/22944 http://upetd.up.ac.za/thesis/available/etd-03032005-121402/ © 2005, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf application/pdf application/pdf University of Pretoria |
| spellingShingle | No keywords available UCTD Serum lactate in canine babesiosis |
| title | Serum lactate in canine babesiosis |
| title_full | Serum lactate in canine babesiosis |
| title_fullStr | Serum lactate in canine babesiosis |
| title_full_unstemmed | Serum lactate in canine babesiosis |
| title_short | Serum lactate in canine babesiosis |
| title_sort | serum lactate in canine babesiosis |
| topic | No keywords available UCTD |
| url | http://hdl.handle.net/2263/22944 http://upetd.up.ac.za/thesis/available/etd-03032005-121402/ |