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Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides
Thesis (PhD (Botany))--University of Pretoria, 2007.
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University of Pretoria
2013
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| _version_ | 1867613569877540864 |
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| access_status_str | Open Access |
| author2 | Meyer, J.J.M. (Jacobus Johannes Marion) |
| author_browse | Meyer, J.J.M. (Jacobus Johannes Marion) |
| author_facet | Meyer, J.J.M. (Jacobus Johannes Marion) |
| collection | Thesis |
| dc_rights_str_mv | © 2007, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD (Botany))--University of Pretoria, 2007. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/25335 |
| institution | University of Pretoria (South Africa) |
| last_indexed | 2026-06-10T12:38:14.452Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/25335 Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides Meyer, J.J.M. (Jacobus Johannes Marion) phatlanem@ul.ac.za Mokwala, Phatlane William Ipomoea adenioides Activity Bioactive Antibacterial Treatment Plants Heartwater Identification Isolation Livestock Compounds petalidium oblongifolium<i/> UCTD Thesis (PhD (Botany))--University of Pretoria, 2007. The general antibacterial activity of Drimia delagoansis, Petalidium oblongifolium and Ipomoea adenioides was determined using selected Gram-positive and Gram-negative bacteria. Only extracts or compounds with high antibacterial activity were then tested against the causative agent of heartwater, Ehlrichia ruminantium, since the latter requires specialised culturing conditions. The crude aqueous extract of D. delagoansis had low antibacterial activity with its highest MIC against Gram-negative bacteria being 20.0 mg ml-1 while the crude methanolic extracts of P. oblongifolium and I. adenioides had their highest antibacterial activity against Gram-negative bacteria at MIC's of 5.0 and 10.0 mg ml-1 respectively. Two compounds were isolated and identified from I. adenioides and an unidentified one was isolated from P. oblongifolium. The two compounds from I. adenioides proved to be caffeic acid with MIC's of 0.8 and 1.0 mg ml-1 against Gram-positive and Gram-negative bacteria respectively; and ethyl caffeate with MIC's of 0.4 and 1.0 mg ml-1 against Gram-positive and Gram-negative bacteria respectively. Synergism between the two compounds increased the respective MIC's to 0.4 and 0.2 µg ml-1 against Gram-positive and Gram-negative bacteria. The unidentified compound isolated from P. oblongifolium had a very low MIC of 2.5 µg ml-1 against E. ruminantium. Plant Science unrestricted 2013-09-06T20:47:28Z 2007-06-08 2013-09-06T20:47:28Z 2007-04-20 2007-06-08 2007-06-08 Thesis Mokwala, P 2007, Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides, PhD thesis, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/25335 > http://hdl.handle.net/2263/25335 http://upetd.up.ac.za/thesis/available/etd-06082007-160159/ © 2007, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf application/pdf application/pdf application/pdf application/pdf University of Pretoria |
| spellingShingle | Ipomoea adenioides Activity Bioactive Antibacterial Treatment Plants Heartwater Identification Isolation Livestock Compounds petalidium oblongifolium<i/> UCTD Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title | Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title_full | Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title_fullStr | Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title_full_unstemmed | Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title_short | Antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from Petalidium Oblongifolium and Ipomoea adenioides |
| title_sort | antibacterial activity of plants that are used in the treatment of heartwater in livestock and the isolation and identification of bioactive compounds from petalidium oblongifolium and ipomoea adenioides |
| topic | Ipomoea adenioides Activity Bioactive Antibacterial Treatment Plants Heartwater Identification Isolation Livestock Compounds petalidium oblongifolium<i/> UCTD |
| url | http://hdl.handle.net/2263/25335 http://upetd.up.ac.za/thesis/available/etd-06082007-160159/ |