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African horse sickness virus dynamics and host responses in naturally infected horses
Dissertation (MSc)--University of Pretoria, 2010.
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| Format: | Thesis |
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University of Pretoria
2013
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| _version_ | 1867613629960945665 |
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| access_status_str | Open Access |
| author2 | Quan, Melvyn |
| author_browse | Quan, Melvyn |
| author_facet | Quan, Melvyn |
| collection | Thesis |
| dc_rights_str_mv | © 2010 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc)--University of Pretoria, 2010. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/25558 |
| institution | University of Pretoria (South Africa) |
| last_indexed | 2026-06-10T12:39:11.828Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/25558 African horse sickness virus dynamics and host responses in naturally infected horses Quan, Melvyn Guthrie, Alan John camillaweyer@gmail.com Weyer, Camilla Theresa African horse sickness virus (AHSV) Culicoides Reoviridae UCTD Orbiviruses Dissertation (MSc)--University of Pretoria, 2010. African horse sickness (AHS) is a life threatening disease of equids caused by African horse sickness virus (AHSV), a member of the genus Orbivirus in the family Reoviridae. The virus is transmitted to horses by midges (Culicoides spp.) and the disease is most prevalent during the time of year, and in areas where the Culicoides spp. are most abundant, namely in late summer in the summer rainfall areas of the country. Whilst the clinical signs and presentation of the disease were well documented by Sir Arnold Theiler (1921), very little is known or documented about AHSV dynamics or the clinical pathological and serological responses of horses to natural infection with AHSV. This dissertation describes the history and current knowledge on AHS, and the methods and results of a prospective study on natural AHSV infection of horses, undertaken between 2009 and 2010 by the Equine Research Centre (ERC) at the University of Pretoria, Faculty of Veterinary Science, Onderstepoort. This study is the first documented study of its nature and included animals of various ages and therefore variable vaccination status. The objectives of the study were to describe the viral dynamics of AHSV infection in horses, to gain a better understanding of the clinical pathological and serological responses to natural AHS infection and to demonstrate early detection of AHS infection in horses under field conditions. Veterinary Tropical Diseases unrestricted 2013-09-06T22:26:08Z 2011-06-21 2013-09-06T22:26:08Z 2011-04-08 2010 2011-06-15 Dissertation Weyer, CT 2010, African horse sickness virus dynamics and host responses in naturally infected horses, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/25558 > E11/281/gm http://hdl.handle.net/2263/25558 http://upetd.up.ac.za/thesis/available/etd-06152011-145610/ © 2010 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | African horse sickness virus (AHSV) Culicoides Reoviridae UCTD Orbiviruses African horse sickness virus dynamics and host responses in naturally infected horses |
| title | African horse sickness virus dynamics and host responses in naturally infected horses |
| title_full | African horse sickness virus dynamics and host responses in naturally infected horses |
| title_fullStr | African horse sickness virus dynamics and host responses in naturally infected horses |
| title_full_unstemmed | African horse sickness virus dynamics and host responses in naturally infected horses |
| title_short | African horse sickness virus dynamics and host responses in naturally infected horses |
| title_sort | african horse sickness virus dynamics and host responses in naturally infected horses |
| topic | African horse sickness virus (AHSV) Culicoides Reoviridae UCTD Orbiviruses |
| url | http://hdl.handle.net/2263/25558 http://upetd.up.ac.za/thesis/available/etd-06152011-145610/ |