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The prevalence of Leptospira serovars causing infection in dogs in South Africa

Dissertation (MSc)--University of Pretoria, 2009.

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Other Authors: Van Vuuren, Moritz
Format: Thesis
Published: University of Pretoria 2013
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access_status_str Open Access
author2 Van Vuuren, Moritz
author_browse Van Vuuren, Moritz
author_facet Van Vuuren, Moritz
collection Thesis
dc_rights_str_mv © 2009, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Dissertation (MSc)--University of Pretoria, 2009.
format Thesis
id oai:repository.up.ac.za:2263/27119
institution University of Pretoria (South Africa)
last_indexed 2026-06-10T12:38:04.955Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2013
publishDateRange 2013
publishDateSort 2013
publisher University of Pretoria
publisherStr University of Pretoria
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source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/27119 The prevalence of Leptospira serovars causing infection in dogs in South Africa Van Vuuren, Moritz Picard, J.A. wandsbeck@mweb.co.za Gatley, Joan Marguerite Infection in dogs L. pyrogenes Leptospira serovars L. canicola South africa UCTD Dissertation (MSc)--University of Pretoria, 2009. Leptospirosis is a disease of global importance with a changing epidemiology in both humans and animals. It is also a significant zoonosis particularly in the developing world. To date there is limited knowledge of the incidence of leptospirosis in dogs in South Africa. This study was undertaken on a subset of dogs in South Africa to determine the presence of leptospiral antibodies to serovars known to infect dogs. Serum samples from both stray and owned dogs from various parts of South Africa were collected and tested against fifteen serovars of Leptospira. Five hundred and thirty samples were tested and twenty-five tested positive to seven different serovars. Nine of the 25 samples tested positive to more than one serovar. The two serovars that were most frequently represented were L. Canicola, which reacted to seventeen sera, and L. Pyrogenes, which reacted to nine sera in all. Currently the only vaccines available in South Africa in different combinations contain either L. Canicola, L. Icterohaemorrhagiae, L. Pomona or L. Grippotyphosa. The results show that the use of vaccines containing L. Canicola is still justifiable in certain regions of the country. However, the presence of antibodies to L. Pyrogenes in several dogs indicates that there is a need to investigate for the presence of antibodies in a larger group of dogs. This would allow vaccine manufacturers to tailor the Leptospira antigens present in vaccines to include those that are prevalent in a particular region or country. Copyright Veterinary Tropical Diseases unrestricted 2013-09-07T10:38:49Z 2010-08-10 2013-09-07T10:38:49Z 2010-04-16 2010-08-10 2010-08-10 Dissertation Gatley, JM 2009, The prevalence of Leptospira serovars causing infection in dogs in South Africa, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/27119 > E10/344/gm http://hdl.handle.net/2263/27119 http://upetd.up.ac.za/thesis/available/etd-08102010-182351/ © 2009, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle Infection in dogs
L. pyrogenes
Leptospira serovars
L. canicola
South africa
UCTD
The prevalence of Leptospira serovars causing infection in dogs in South Africa
title The prevalence of Leptospira serovars causing infection in dogs in South Africa
title_full The prevalence of Leptospira serovars causing infection in dogs in South Africa
title_fullStr The prevalence of Leptospira serovars causing infection in dogs in South Africa
title_full_unstemmed The prevalence of Leptospira serovars causing infection in dogs in South Africa
title_short The prevalence of Leptospira serovars causing infection in dogs in South Africa
title_sort prevalence of leptospira serovars causing infection in dogs in south africa
topic Infection in dogs
L. pyrogenes
Leptospira serovars
L. canicola
South africa
UCTD
url http://hdl.handle.net/2263/27119
http://upetd.up.ac.za/thesis/available/etd-08102010-182351/