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Development of a method to create subject specific cochlear models for electric hearing
Dissertation (MEng)--University of Pretoria, 2009.
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| Format: | Thesis |
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University of Pretoria
2013
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| _version_ | 1867613659783495680 |
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| access_status_str | Open Access |
| author2 | Hanekom, J.J. (Johannes Jurgens) |
| author_browse | Hanekom, J.J. (Johannes Jurgens) |
| author_facet | Hanekom, J.J. (Johannes Jurgens) |
| collection | Thesis |
| dc_rights_str_mv | © 2009 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MEng)--University of Pretoria, 2009. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/29073 |
| institution | University of Pretoria (South Africa) |
| last_indexed | 2026-06-10T12:39:39.821Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/29073 Development of a method to create subject specific cochlear models for electric hearing Hanekom, J.J. (Johannes Jurgens) Hanekom, Tania tiaan.malherbe@up.ac.za Malherbe, Tiaan Krynauw 3d model Subject specific Brain stem response data μ-ct scan Eabr Fem model Neural model Cochlear model UCTD Dissertation (MEng)--University of Pretoria, 2009. Cochlear implants are electronic devices intended for restoring hearing to the profoundly deaf. Unfortunately the degree of restored hearing varies greatly between subjects. To investigate some of the mechanisms that determine this variability, mathematical models of the auditory system are used. The level of detail that these models incorporate varies greatly. The present study describes the development of a method to create high detail, subject specific cochlea models. μ-CT scans and photomicrographs were used to obtain the morphology and histology of a specific guinea pig cochlea. A 3D model was constructed from this data and the finite element method was used to determine the potential distribution inside the cochlea. The potential distribution was calculated for different stimulus protocols applied to different modelled electrodes. A neuron model was then used to obtain neural excitation profiles. The modelled excitation profiles were compared to data from literature and it was found that this model is valid and can be used as a tool in electric hearing research. The model output was also compared to brainstem response data from the specific subject to assess the degree to which this model can predict brain stem data from a specific subject. Possible improvements to the model were also discussed. Electrical, Electronic and Computer Engineering unrestricted 2013-09-07T14:48:06Z 2011-11-01 2013-09-07T14:48:06Z 2009-09-02 2009 2011-10-26 Dissertation Malherbe, TK 2009 Development of a method to create subject specific cochlear models for electric hearing, MEng dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/29073 > E1470/ag http://hdl.handle.net/2263/29073 http://upetd.up.ac.za/thesis/available/etd-10262011-162320/ © 2009 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | 3d model Subject specific Brain stem response data μ-ct scan Eabr Fem model Neural model Cochlear model UCTD Development of a method to create subject specific cochlear models for electric hearing |
| title | Development of a method to create subject specific cochlear models for electric hearing |
| title_full | Development of a method to create subject specific cochlear models for electric hearing |
| title_fullStr | Development of a method to create subject specific cochlear models for electric hearing |
| title_full_unstemmed | Development of a method to create subject specific cochlear models for electric hearing |
| title_short | Development of a method to create subject specific cochlear models for electric hearing |
| title_sort | development of a method to create subject specific cochlear models for electric hearing |
| topic | 3d model Subject specific Brain stem response data μ-ct scan Eabr Fem model Neural model Cochlear model UCTD |
| url | http://hdl.handle.net/2263/29073 http://upetd.up.ac.za/thesis/available/etd-10262011-162320/ |