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Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique

Dissertation (MSc (Veterinary Science))--University of Pretoria, 2008.

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Other Authors: Van den Bossche, Peter
Format: Thesis
Language:English
Published: University of Pretoria 2013
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access_status_str Open Access
author2 Van den Bossche, Peter
author_browse Van den Bossche, Peter
author_facet Van den Bossche, Peter
collection Thesis
dc_rights_str_mv © University of Pretoria
description Dissertation (MSc (Veterinary Science))--University of Pretoria, 2008.
format Thesis
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institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:36:09.504Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2013
publishDateRange 2013
publishDateSort 2013
publisher University of Pretoria
publisherStr University of Pretoria
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source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/30765 Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique Van den Bossche, Peter hevet@zebra.uem.mz Penzhorn, Barend Louis Tchamo, Cesaltina da Conceiçao Lopes Menete UCTD Pathogenicity Dissertation (MSc (Veterinary Science))--University of Pretoria, 2008. A study was conducted to determine the impact of infections with Trypanosoma congolense on various variables (including hematological and biochemical parameters) of South African Boer goats kept on various planes of nutrition. Sixteen goats with eight months old divided into four groups and weighing on average 12 kg were used in the experiments. Two groups (of four goats each) were infected with a T. congolense isolated in the Matutuine District of Mozambique. One group (of four goats) was kept on a low energy budget (9.72 MJ of metabolizable energy per kg and 0.16 kg of digestible protein per kg) whereas another group (of four goats) was kept on a high-energy budget (9.72 MJ of metabolizable energy per kg and 0.09 kg of digestible protein per kg). Two uninfected control groups kept on a low or high-energy budget were included in the experiment. In each of the experimental groups, the parasitemia, packed cell volume (PCV), the hemoglobin level, the red blood cell count ( RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), the total serum protein level (TSP), the total bilirubin level, the serum aspartate aminotransferase level (AST), the inorganic phosphate level (SIP), the serum gama glutamyltransferase level (GGT), the serum urea level, the creatinin and the creatin kinase ( CK) levels, the body temperature and weighs were monitored and compared during the pre-patent from day -13 to 7 and during the chronic one from day 22 to 56. The first peak of parasitemia occurred earlier in infected goats kept on a low energy diet. Throughout the observation period, infection with T. congolense and diet had no significant effects on body weight. On the other hand, PCV, RBC counts reduced in both groups of infected goats. The pre-infection phase urea levels were higher in the animals (infected and control) kept on a high-energy diet. No significant changes were observed in the plasma of Albumin, AST, Creatinin, GGT, Globulin, SIP and TSP levels as a result of diet and/or infection with T. congolense. These results suggest that the infection with the Mozambican isolate of T. congolense, which was used in this study, induces a mild infection with no or minimal effect on the health goats even when kept on a low energy plane of nutrition. Veterinary Tropical Diseases Restricted Veterinary Science 2013-09-09T07:29:35Z 2008-04-24 2013-09-09T07:29:35Z 2007-11-23 2008-04-24 2008-04-21 Dissertation Pretoria http://hdl.handle.net/2263/30765 http://upetd.up.ac.za/thesis/available/etd-04212008-143822/ en © University of Pretoria application/pdf application/pdf University of Pretoria
spellingShingle UCTD
Pathogenicity
Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title_full Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title_fullStr Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title_full_unstemmed Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title_short Evaluation of the pathogenicity in goats of Trypanosoma Congolense from Matutuine, Mozambique
title_sort evaluation of the pathogenicity in goats of trypanosoma congolense from matutuine mozambique
topic UCTD
Pathogenicity
url http://hdl.handle.net/2263/30765
http://upetd.up.ac.za/thesis/available/etd-04212008-143822/