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Modelling subject-specific electrically evoked auditory neural responses in the guinea pig
Dissertation (MEng)--University of Pretoria, 2012.
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| Format: | Thesis |
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2013
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| _version_ | 1867613486051229696 |
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| access_status_str | Open Access |
| author2 | Hanekom, Tania |
| author_browse | Hanekom, Tania |
| author_facet | Hanekom, Tania |
| collection | Thesis |
| dc_rights_str_mv | © 2012 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria E13/4/726/ |
| description | Dissertation (MEng)--University of Pretoria, 2012. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/30953 |
| institution | University of Pretoria (South Africa) |
| last_indexed | 2026-06-10T12:36:54.588Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/30953 Modelling subject-specific electrically evoked auditory neural responses in the guinea pig Hanekom, Tania Hanekom, J.J. (Johannes Jurgens) Govindasamy, Ramana UCTD Dissertation (MEng)--University of Pretoria, 2012. The degree of hearing restoration provided by the cochlear implant is prone to inter-subject variance. The objective of this study is to account for some of the factors influencing this through a subject-specific model of the guinea pig inner ear. Electrically evoked auditory neural responses, a common measure of threshold activity, are used to quantify the accuracy of the model. The model expands on the existing guinea pig subject-specific model through the implementation of added parameters. It was found that modeling the return electrode, silicon carrier and hook region has the greatest effect on improving the accuracy of the model. These findings provide insight into the various parameters that affect neural excitation behaviour in the electrically stimulated auditory system and also lay the foundation for the development of subject-specific human models. It is expected that these models could potentially provide a tool to individualise implant parameters. Afrikaans: Die vlak van gehoorherwinning wat deur kogleêre inplantings verskaf word, wissel van persoon tot persoon. Die doel van hierdie navorsing is om faktore onderliggend aan hierdie variasie te ondersoek deur middel van 'n onderwerpspesifieke model van die marmotkoglea. Elektries-opgewekte gehoorsenuweereaksies, wat 'n kritieke stap in die gehoorherwinningsproses verteenwoordig, is gebruik om die akkuraatheid van die model te meet. Die model brei uit op die bestaande onderwerpspesifieke model deur bykomende veranderlikes te implemteer. Die modellering van die terugkeerelektrode, die silikoondraer en die haakarea het die meeste bygedra tot die verbetering van die model. Hierdie bevindinge werp lig op die verskeie veranderlikes wat die gedrag van senuwees in die elektries-gestimuleerde gehoorstelsel beïnvloed en lê 'n grondslag vir die ontwikkeling van onderwerpspesifieke modelle van menskogleas. Sulke modelle kan bydra tot gereedskap vir die berekening van veranderlikes vir individuele inplantinggebruikers. Electrical, Electronic and Computer Engineering MEng Unrestricted 2013-09-09T07:51:53Z 2013-06-28 2013-09-09T07:51:53Z 2012-04-15 2012 2013-06-21 Dissertation Govindasamy, R 2012, Modelling subject-specific electrically evoked auditory neural responses in the guinea pig, MEng Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/30953> E13/4/726/gm http://hdl.handle.net/2263/30953 http://upetd.up.ac.za/thesis/available/etd-06212013-181022/ © 2012 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria E13/4/726/ application/pdf |
| spellingShingle | UCTD Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title | Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title_full | Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title_fullStr | Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title_full_unstemmed | Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title_short | Modelling subject-specific electrically evoked auditory neural responses in the guinea pig |
| title_sort | modelling subject specific electrically evoked auditory neural responses in the guinea pig |
| topic | UCTD |
| url | http://hdl.handle.net/2263/30953 http://upetd.up.ac.za/thesis/available/etd-06212013-181022/ |