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Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses
Dissertation (MMedVet)--University of Pretoria, 2013.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2014
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| _version_ | 1867613442468216832 |
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| access_status_str | Open Access |
| author2 | Saulez, Montague Newton |
| author_browse | Saulez, Montague Newton |
| author_facet | Saulez, Montague Newton |
| collection | Thesis |
| dc_rights_str_mv | © 2013 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MMedVet)--University of Pretoria, 2013. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/36795 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:12.984Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/36795 Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses Saulez, Montague Newton emmajm45@hotmail.com Sanz, Macarena G. McConnell, Emma Jane Anaesthesia Cerebral oximeter Horses Hypercapnoea Near-infrared spectroscopy Neuromonitoring UCTD Dissertation (MMedVet)--University of Pretoria, 2013. This dissertation focuses on the use of near-infrared spectroscopy (NIRS) to identify trends in regional cerebral oxygen saturation (rSO2) in both conscious and anaesthetised healthy horses. A cerebral/somatic oximeter sensor recorded rSO2 from the dorsal sagittal sinus of 6 healthy horses. Values for rSO2, arterial and venous oxygen and carbon dioxide tensions (PaO2, PvO2, PaCO2 and PvCO2 respectively), along with arteriovenous oxygen saturations (SavO2) were recorded in unsedated (recording period [RP] 1), sedated (RP2), and anaesthetised horses (RP3-5); and during recovery (RP6-8). During anaesthesia, horses were ventilated to achieve states of normo- (RP3), hyper- (RP4) and hypocapnoea (RP5). Overall mean ± s.d. values for rSO2, PaO2, PvO2, PaCO2, SavO2 and mean arterial pressure (MAP) varied significantly by RP. Significant decreases in rSO2 were identified between RP1 and the post-anaesthetic periods however no significant differences in rSO2 values were identified between RP1 and the intra-anaesthesia periods. Regional cerebral oxygen saturation was significantly correlated with PaO2, PvO2 and SavO2. No correlation was identified between rSO2 and lactate concentration. This is the first study to identify trends in rSO2 in horses using NIRS. A significant positive correlation was identified between rSO2 and PvO2, suggesting that alterations in cerebral oxygenation may be reflected in jugular PvO2. Results of this study demonstrate that NIRS can be used during general anaesthesia to monitor trends in rSO2 in healthy horses, and has the potential to alert clinicians to cerebral desaturation events when used in a clinical setting. gm2014 Companion Animal Clinical Studies unrestricted 2014-02-26T11:19:04Z 2014-02-26T11:19:04Z 2013-09-06 2013 Dissertation McConnell, EJ 2013, Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses, MMedVet dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/36795> E13/9/1135/gm http://hdl.handle.net/2263/36795 en © 2013 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Anaesthesia Cerebral oximeter Horses Hypercapnoea Near-infrared spectroscopy Neuromonitoring UCTD Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title | Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title_full | Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title_fullStr | Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title_full_unstemmed | Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title_short | Use of near-infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| title_sort | use of near infrared spectroscopy to identify trends in regional cerebral oxygen saturation in horses |
| topic | Anaesthesia Cerebral oximeter Horses Hypercapnoea Near-infrared spectroscopy Neuromonitoring UCTD |
| url | http://hdl.handle.net/2263/36795 |