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Remediation of instability in Best Linear Unbiased Prediction

Thesis (PhD)--University of Pretoria, 2013.

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Other Authors: Roux, Carl Z.
Format: Thesis
Language:English
Published: University of Pretoria 2014
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author2 Roux, Carl Z.
author_browse Roux, Carl Z.
author_facet Roux, Carl Z.
collection Thesis
dc_rights_str_mv © 2013 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Thesis (PhD)--University of Pretoria, 2013.
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institution University of Pretoria (South Africa)
language English
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publisher University of Pretoria
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spelling oai:repository.up.ac.za:2263/40245 Remediation of instability in Best Linear Unbiased Prediction Roux, Carl Z. karen.eatwell@gmail.com Verryn, Stephen David Eatwell, Karen Anne Family component of variance Phenotypic variance Additive genetic variance Narrow-sense heritability Fourth generation of breeding Third generation of breeding Second generation of breeding Parental or first generation of breeding Randomized Complete Block experimental design Diameter at Breast Height Best Linear Unbiased Prediction Best Linear Prediction Analysis of variance UCTD Thesis (PhD)--University of Pretoria, 2013. In most breeding programmes breeders use phenotypic data obtained in breeding trials to rank the performance of the parents or progeny on pre-selected performance criteria. Through this ranking the best candidates are identified and selected for breeding or production purposes. Best Linear Unbiased Prediction (BLUP), is an efficient selection method to use, combining information into a single index. Unbalanced or messy data is frequently found in tree breeding trial data. Trial individuals are related and a degree of correlation is expected between individuals over sites, which can lead to collinearity in the data which may lead to instability in certain selection models. A high degree of collinearity may cause problems and adversely affect the prediction of the breeding values in a BLUP selection index. Simulation studies have highlighted that instability is a concern and needs to be investigated in experimental data. The occurrence of instability, relating to collinearity, in BLUP of tree breeding data and possible methods to deal with it were investigated in this study. Case study data from 39 forestry breeding trials (three generations) of Eucalyptus grandis and 20 trials of Pinus patula (two generations) were used. A series of BLUP predictions (rankings) using three selection traits and 10 economic weighting sets were made. Backward and forward prediction models with three different matrix inversion techniques (singular value decomposition, Gaussian elimination - partial and full pivoting) and an adapted ridge regression technique were used in calculating BLUP indices. A Delphi and Clipper version of the same BLUP programme which run with different computational numerical precision were used and compared. Predicted breeding values (forward prediction) were determined in the F1 and F2 E. grandis trials and F1 P. patula trials and realised breeding performance (backward prediction) was determined in the F2 and F3 E. grandis trials and F2 P. patula trials. The accuracy (correlation between the predicted breeding values and realised breeding performance) was estimated in order to assess the efficiency of the predictions and evaluate the different matrix inversion methods. The magnitude of the accuracy (correlations) was found to mostly be of acceptable magnitude when compared to the heritability of the compound weighted trait in the F1F2 E. grandis scenarios. Realised genetic gains were also calculated for each method used. Instability was observed in both E. grandis and P. patula breeding data in the study, and this may cause a significant loss in realised genetic gains. Instability can be identified by examining the matrix calculated from the product of the phenotypic covariance matrix with its inverse, for deviations from the expected identity pattern. Results of this study indicate that it may not always be optimal to use a higher numerical precision programme when there is collinearity in the data and instability in the matrix calculations. In some cases, where there is a large amount of collinearity, the use of a higher precision programme for BLUP calculations can significantly increase or decrease the accuracy of the rankings. The different matrix inversion techniques particularly SVD and adapted ridge regression did not perform much better than the full pivoting technique. The study found that it is beneficial to use the full pivoting Gaussian elimination matrix inversion technique in preference to the partial pivoting Gaussian elimination matrix inversion technique for both high and lower numerical precision programmes. gm2014 Genetics unrestricted 2014-06-17T13:05:46Z 2014-06-17T13:05:46Z 2014-04-09 2013 Thesis Eatwell, KA 2013, Lowies, GE 2012, 'The role of behavioural aspects in investment decision-making by listed property fund managers in South Africa', PhD thesis, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/40245> D14/4/112/gm http://hdl.handle.net/2263/40245 en © 2013 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle Family component of variance
Phenotypic variance
Additive genetic variance
Narrow-sense heritability
Fourth generation of breeding
Third generation of breeding
Second generation of breeding
Parental or first generation of breeding
Randomized Complete Block experimental design
Diameter at Breast Height
Best Linear Unbiased Prediction
Best Linear Prediction
Analysis of variance
UCTD
Remediation of instability in Best Linear Unbiased Prediction
title Remediation of instability in Best Linear Unbiased Prediction
title_full Remediation of instability in Best Linear Unbiased Prediction
title_fullStr Remediation of instability in Best Linear Unbiased Prediction
title_full_unstemmed Remediation of instability in Best Linear Unbiased Prediction
title_short Remediation of instability in Best Linear Unbiased Prediction
title_sort remediation of instability in best linear unbiased prediction
topic Family component of variance
Phenotypic variance
Additive genetic variance
Narrow-sense heritability
Fourth generation of breeding
Third generation of breeding
Second generation of breeding
Parental or first generation of breeding
Randomized Complete Block experimental design
Diameter at Breast Height
Best Linear Unbiased Prediction
Best Linear Prediction
Analysis of variance
UCTD
url http://hdl.handle.net/2263/40245