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Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study
Dissertation (MSc)--University of Pretoria, 2014.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2015
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| _version_ | 1867613459027329024 |
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| access_status_str | Open Access |
| author2 | Boy, Sonja Catharina |
| author_browse | Boy, Sonja Catharina |
| author_facet | Boy, Sonja Catharina |
| collection | Thesis |
| dc_rights_str_mv | © 2014 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc)--University of Pretoria, 2014. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/43309 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:28.597Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/43309 Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study Boy, Sonja Catharina christylanadavidson@gmail.com Richter, Karin Louise Davidson, Christy Lana Human papillomavirus (HPV) Oropharyngeal squamous cell carcinoma Sexual partners Tobacco use Alcohol use UCTD Dissertation (MSc)--University of Pretoria, 2014. Oral human papillomavirus (HPV) infection and its association with head and neck cancers (HNCs) have been established by many studies. The characteristics of HPV-associated HNCs are distinguishable from those of non HPV-associated HNCs. HPV-associated HNCs are related to sexual behaviour, particularly the lifetime number of oral sex partners. The oral and oropharyngeal HPV epidemiology in South African men has not yet been researched. The objective of this study was to determine the oral and oropharyngeal HPV strain prevalence and associated factors in a selected male population in Pretoria, South Africa. Male factory workers were recruited on a voluntary basis to be part of this study. Oral rinse and gargle samples were tested for 37 HPV types using the HPV linear array genotyping kit (Roche Molecular System). A questionnaire was utilised to obtain information regarding age, medical conditions, substance and alcohol use and sexual behaviour. HIV testing was optional. The HPV prevalence was 5.6% among the men (n=125) aged 17-64 years. High risk HPV (hrHPV) types 16 and 68 were found in two men. Amongst the majority of the participants oral sex seemed to be an uncommon practice however, those participants with hrHPV did practice oral sex. A statistically significant association between HPV infection and an increased number of sexual partners (p=0.027) was seen but not between substance use, HIVstatus or clinical mucosal pathology. Considering the oral and oropharyngeal HPV prevalence found in this study compared to those reported in other countries. It is therefore proposed that a larger nationwide study be conducted to give a more representative view of the burden of oral and oropharyngeal HPV infection in South Africa. lk2014 Community Dentistry MSc Unrestricted 2015-01-19T12:13:27Z 2015-01-19T12:13:27Z 2014/12/12 2014 Dissertation Davidson, CL 2014, Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/43309> M14/9/368 http://hdl.handle.net/2263/43309 en © 2014 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | Human papillomavirus (HPV) Oropharyngeal squamous cell carcinoma Sexual partners Tobacco use Alcohol use UCTD Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title | Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title_full | Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title_fullStr | Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title_full_unstemmed | Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title_short | Prevalence of oral and oropharyngeal human papillomavirus (HPV) in a sample of selected South African males : a pilot study |
| title_sort | prevalence of oral and oropharyngeal human papillomavirus hpv in a sample of selected south african males a pilot study |
| topic | Human papillomavirus (HPV) Oropharyngeal squamous cell carcinoma Sexual partners Tobacco use Alcohol use UCTD |
| url | http://hdl.handle.net/2263/43309 |