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Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study
Dissertation (MPH)--University of Pretoria, 2015.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2015
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| _version_ | 1867613457398890496 |
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| access_status_str | Open Access |
| author2 | Van Zyl, Danie G. |
| author_browse | Van Zyl, Danie G. |
| author_facet | Van Zyl, Danie G. |
| collection | Thesis |
| dc_rights_str_mv | © 2015 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MPH)--University of Pretoria, 2015. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/46144 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:27.243Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/46144 Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study Van Zyl, Danie G. Rheeder, Paul Ngassa Piotie, Patrick UCTD Diabetic Nephropathy Estimated glomerular filtration rate Microalbuminuria Health sciences theses SDG-03 Health sciences theses SDG-17 Dissertation (MPH)--University of Pretoria, 2015. Objective: The aim of this study was to determine the prevalence of micro- or macroalbuminuria among type 1 and type 2 diabetic patients and to examine the relationship with diabetes control parameters: haemoglobin A1C (HbA1C), blood pressure (BP) and lipids. Design: Analytical cross-sectional study. Setting and subjects: The study consisted of 754 patients with either type 1 or type 2 diabetes mellitus, attending a diabetic clinic at the Kalafong Hospital in Pretoria, South Africa. Outcome measures: Micro- or macroalbuminuria and estimated glomerular filtration rate (eGFR). Results: Of all patients, 88.9% had HbA1C > 7%, and 81% had low-density lipoprotein (LDL) cholesterol ≥1.8 mmol/l. Overall prevalence of micro- or macroalbuminuria was 33.6%. Logistic regression revealed that HbA1C, duration of diabetes, systolic BP, male sex and triglycerides predicted microalbuminuria. Conclusion: The prevalence of micro- or macroalbuminuria in this study falls within the ranges of what has been previously reported in Africa. In all patients, HbA1C and duration of diabetes were the strongest predictors of microalbuminuria, and age was the strongest predictor of a low eGFR. Diabetes was poorly controlled, making the progression to end-stage renal failure a real concern in these patients. tm2015 em2026 School of Health Systems and Public Health (SHSPH) MPH Unrestricted SDG-03: Good health and well-being SDG-17: Partnerships for the goals 2015-07-02T11:06:58Z 2015-07-02T11:06:58Z 2015/04/24 2015 Dissertation Ngassa Piotie, P 2015, Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study, MPH Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/46144> A2015 http://hdl.handle.net/2263/46144 en © 2015 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Diabetic Nephropathy Estimated glomerular filtration rate Microalbuminuria Health sciences theses SDG-03 Health sciences theses SDG-17 Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title | Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title_full | Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title_fullStr | Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title_full_unstemmed | Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title_short | Diabetic nephropathy in a tertiary clinic in South Africa, a cross-sectional study |
| title_sort | diabetic nephropathy in a tertiary clinic in south africa a cross sectional study |
| topic | UCTD Diabetic Nephropathy Estimated glomerular filtration rate Microalbuminuria Health sciences theses SDG-03 Health sciences theses SDG-17 |
| url | http://hdl.handle.net/2263/46144 |