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Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale
Dissertation (MSc)--University of Pretoria, 2014.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2015
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| _version_ | 1867613718678863872 |
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| access_status_str | Open Access |
| author2 | Schulman, Martin L. |
| author_browse | Schulman, Martin L. |
| author_facet | Schulman, Martin L. |
| collection | Thesis |
| dc_rights_str_mv | © 2015 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Dissertation (MSc)--University of Pretoria, 2014. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/46265 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:40:36.114Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/46265 Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale Schulman, Martin L. Page, Patrick Collin Guthrie, Alan John Ganswindt, Andre Badenhorst, Marcha UCTD Equine herpesvirus Physiological stress Sales consignment Faecal glucocorticoid metabolite (fGCM) Horses Dissertation (MSc)--University of Pretoria, 2014. Commingling of horses from various populations, together with physiological stress associated with transport and confinement at a sales complex, may be associated with detection and transmission of equine herpesvirus type-1 (EHV-1) and -4 (EHV-4). This prospective cohort study aimed to investigate the currently undefined prevalence of EHV-1 and -4 in young Thoroughbreds at an auction sale in South Africa, and associations between clinical signs, physiological stress and viral detection. Ninety, two-year old Thoroughbreds (51 colts, 39 fillies) were consigned from eight farms and sampled at a South African auction sale. The horses were monitored for pyrexia and nasal discharge. Nasal swabs were collected for quantitative polymerase chain reaction (qPCR) assay to detect EHV-1 and -4 and faecal samples were collected for enzyme immunoassay (EIA) to determine faecal glucocorticoid metabolite (FGM) concentrations. EHV-4 nucleic acid was detected in some and EHV-1 nucleic acid in none of the population. Pyrexia and nasal discharge were poor indicators of EHV-4 status. Variation in FGM concentrations was best explained by transportation and preparation for auction. Peaks in EHV-4 detection and increases in FGM concentrations were identified shortly post-arrival and on the first day of auction. Temporal changes in FGM concentrations of horses from individual farms showed two distinct patterns: Pattern A (biphasic peaks) and Pattern B (single peak). It was concluded that sales consignment was associated with some EHV-4 nucleic acid detection and distinctive physiological stress patterns in this population of young Thoroughbreds. tm2015 Companion Animal Clinical Studies MSc Unrestricted 2015-07-02T11:08:32Z 2015-07-02T11:08:32Z 2015/04/22 2014 Dissertation Badenhorst, M 2014, Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/46265> A2015 6507085906 G-9856-2014 7006535470 J-6375-2013 0000-0001-7729-9918 http://hdl.handle.net/2263/46265 en © 2015 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Equine herpesvirus Physiological stress Sales consignment Faecal glucocorticoid metabolite (fGCM) Horses Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title | Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title_full | Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title_fullStr | Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title_full_unstemmed | Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title_short | Detection of equine herpesvirus -4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale |
| title_sort | detection of equine herpesvirus 4 and physiological stress patterns in young thoroughbreds consigned to a south african auction sale |
| topic | UCTD Equine herpesvirus Physiological stress Sales consignment Faecal glucocorticoid metabolite (fGCM) Horses |
| url | http://hdl.handle.net/2263/46265 |