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Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review
Mini Dissertation (MA)--University of Pretoria, 2015.
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| Other Authors: | |
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2016
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| _version_ | 1867613661358456832 |
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| access_status_str | Open Access |
| author2 | Cassimjee, Nafisa |
| author_browse | Cassimjee, Nafisa |
| author_facet | Cassimjee, Nafisa |
| collection | Thesis |
| dc_rights_str_mv | © 2016 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Mini Dissertation (MA)--University of Pretoria, 2015. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/53414 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:39:41.715Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/53414 Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review Cassimjee, Nafisa angamia.shareeka@gmail.com Angamia, Shareeka UCTD Mini Dissertation (MA)--University of Pretoria, 2015. The purpose of this study was to review the neuropsychological outcomes of bed nucleus of the stria terminalis (BNST) deep brain stimulation (DBS) for treatment resistant depression (TRD). In addition, this study would report the mood outcomes of the treatment. Previous research endeavours have explored the safety and efficacy of available treatment methods for TRD as well as the clinical outcomes. Studies have observed antidepressant effects in patients treated with DBS for TRD. However, limited research exists regarding neuropsychological outcomes. In this study a brief history of the patient was provided. A battery of neuropsychological assessments were administered to one patient by a trained psychologist at baseline and at 6, 9 and 12 month s post-DBS in order to assess cognitive functioning. Neuropsychological testing covered the cognitive domains of attention, memory, executive functions, language, mental processing speed, verbal fluency and visuospatial/construction abilities. The results of these assessments were compared to available normative data and retrospectively reviewed. No adverse cognitive effects were observed following surgery, onset and maintenance of DBS when test results from baseline were compared to results at the 12 month interval. Areas of cognition that were impaired or below average at baseline improved at follow-up. However, attention and visuospatial/construction abilities, did not improve to normative levels at 12 months. Though no statistical analysis were conducted these results lend support for the cognitive safety of DBS of the bed nucleus of the stria terminalis for TRD. Psychology MA Unrestricted 2016-06-27T12:17:31Z 2016-06-27T12:17:31Z 2016-04-13 2015 Mini Dissertation Angamia, S 2015, Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review, MA Mini Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/53414> A2016 http://hdl.handle.net/2263/53414 en © 2016 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title | Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title_full | Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title_fullStr | Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title_full_unstemmed | Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title_short | Longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression : a retrospective review |
| title_sort | longitudinal neuropsychological outcomes of deep brain stimulation for treatment resistant depression a retrospective review |
| topic | UCTD |
| url | http://hdl.handle.net/2263/53414 |