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Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity
Thesis (PhD)--University of Pretoria, 2017.
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| Format: | Thesis |
| Language: | English |
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University of Pretoria
2018
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| _version_ | 1867613453135380480 |
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| access_status_str | Open Access |
| author2 | Oosthuizen, Marinda C. |
| author_browse | Oosthuizen, Marinda C. |
| author_facet | Oosthuizen, Marinda C. |
| collection | Thesis |
| dc_rights_str_mv | © 2018 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. |
| description | Thesis (PhD)--University of Pretoria, 2017. |
| format | Thesis |
| id | oai:repository.up.ac.za:2263/65485 |
| institution | University of Pretoria (South Africa) |
| language | English |
| last_indexed | 2026-06-10T12:36:23.211Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | University of Pretoria |
| publisherStr | University of Pretoria |
| record_format | dspace |
| source_str | UPSpace — University of Pretoria Institutional Repository |
| spelling | oai:repository.up.ac.za:2263/65485 Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity Oosthuizen, Marinda C. mantungwa98@gmail.com Collins, Nicola E. Brayton, Kelly A. Khumalo, Zamantungwa Thobeka Happiness UCTD Thesis (PhD)--University of Pretoria, 2017. In summary, this study presents a novel genetic test based on msp1aS to discriminate strains of A. centrale and shows that the vaccine strain is found widely distributed across South Africa and in animals that do not have a history of vaccination. Results also indicate the significance of wildlife as a reservoir host for A. centrale. The phylogenetic analysis presented, together with differences in genome architecture, msp1?/msp1aS gene sequence, and the biology of tick transmissibility, provided sufficient divergence between A. centrale and A. marginale to classify them as separate species. The findings from this study furthermore suggested that R. evertsi evertsi, R. appendiculatus and R. microplus may be responsible for transmission of A. centrale. This study contributes greatly to the description and the taxonomic status of A. centrale. Veterinary Tropical Diseases PhD Unrestricted 2018-07-13T06:48:19Z 2018-07-13T06:48:19Z 2018/04/20 2017 Thesis Khumalo, ZTH 2017, Anaplasma centrale in South Africa: occurrence phylogeny and genetic diversity, PhD Thesis, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/65485> A2018 http://hdl.handle.net/2263/65485 en © 2018 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria |
| spellingShingle | UCTD Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title | Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title_full | Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title_fullStr | Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title_full_unstemmed | Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title_short | Anaplasma centrale in South Africa : occurrence phylogeny and genetic diversity |
| title_sort | anaplasma centrale in south africa occurrence phylogeny and genetic diversity |
| topic | UCTD |
| url | http://hdl.handle.net/2263/65485 |