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Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area

Dissertation (MSc)--University of Pretoria, 2017.

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Other Authors: Oosthuizen, Marinda C.
Format: Thesis
Language:English
Published: University of Pretoria 2018
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access_status_str Open Access
author2 Oosthuizen, Marinda C.
author_browse Oosthuizen, Marinda C.
author_facet Oosthuizen, Marinda C.
collection Thesis
dc_rights_str_mv © 2018 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
description Dissertation (MSc)--University of Pretoria, 2017.
format Thesis
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institution University of Pretoria (South Africa)
language English
last_indexed 2026-06-10T12:37:03.713Z
license_str Other — see source repository
provenance_str_mv Harvested via OAI-PMH from UPSpace — University of Pretoria Institutional Repository
publishDate 2018
publishDateRange 2018
publishDateSort 2018
publisher University of Pretoria
publisherStr University of Pretoria
record_format dspace
source_str UPSpace — University of Pretoria Institutional Repository
spelling oai:repository.up.ac.za:2263/67985 Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area Oosthuizen, Marinda C. liesl.deboni@gmail.com Brayton, Kelly A. De Boni, Liesl UCTD Unrestricted Tick-borne haemoparasites Rodents Ectoparasites Ticks Veterinary science theses SDG-03 Veterinary science theses SDG-11 SDG-11: Sustainable cities and communities SDG-03: Good health and well-being Dissertation (MSc)--University of Pretoria, 2017. In 2013, a disease survey of people in the Mnisi community, Bushbuckridge, Mpumalanga, South Africa revealed a surprisingly high level of exposure to tick bite fever, Bartonella, Q fever and leptospirosis. This indicated the need to educate the community about ectoparasites, exposure to rodents and general hygiene. In addition, the potential contribution of rodent pathogen transmission to human febrile illnesses is considered a public health concern and warrants further investigation. Most human tick-borne diseases are considered emerging diseases because the number of reported cases annually is increasing. This is probably due to ecological changes, increased awareness and an increased number of susceptible individuals in the global population. Conservation efforts have increased numbers and ranges of host animals which maintain the infected tick population and humans are increasingly encroaching into tick dense areas. Thus, humans are more exposed to tick-borne infectious diseases. Increased awareness by doctors and the public has also contributed to the increased reporting of human tick-borne disease. With major medical advancements, there is an increased proportion of the population that is more susceptible to these infectious diseases. Vector-borne parasitic zoonoses are an important aspect of a constantly changing world because they are also constantly adapting to their new circumstances. Infectious organisms can change virulence, hosts and vectors. These diseases are, therefore, very much a part of the future. With new advances in molecular biology, detection of infectious diseases is constantly improving. The economic impact and losses due to vector-borne diseases are wide and felt at both the human health and animal health levels. Losses occur due to the cost of human illness, deaths, reduced animal production and costs to control or prevent disease. In developing countries where animals are relied on for work, transportation and nutrition, the losses are more profound. The order Rodentia is the most abundant and diversified order. Rodents are distributed all over the world except for Antarctica. They often live in close contact with humans, their farm animals and their pets. Rodents pose a threat to humans in several ways. Not only do they act as reservoirs for infectious diseases and serve as hosts for vectors, they also compete globally with us for food, causing serious pre-harvest damage to cereals every year. Examples of rodent-borne human illnesses include rickettsiosis, babesiosis, human granulocytic anaplasmosis, leptospirosis, bartonellosis, tick-borne relapsing fever, Lyme disease and Q fever. More information about these diseases and their impact on public health in an African context is needed. This mini dissertation is divided into two parts. The first is a narrative literature review on what is known about the common rodent-borne bacterial and parasitic pathogens which have an important impact on public health and their relevance in Africa. The current knowledge is described and recommendations for further research are given. The second part is a laboratory project which focused on determining the incidence of selected tickborne pathogens found in wild rodent species in the Mnisi community, a livestock-wildlifehuman interface area in South Africa. Forty wild rodent blood samples underwent a broadbased screening approach using reverse line blot (RLB) hybridization and a more specific approach using quantitative real-time PCR (qPCR) techniques. Veterinary Tropical Diseases MSc 2018-12-05T08:06:20Z 2018-12-05T08:06:20Z 2009/06/18 2017 Dissertation de Boni, L 2017, Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/67985> S2018 http://hdl.handle.net/2263/67985 en © 2018 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. application/pdf University of Pretoria
spellingShingle UCTD
Unrestricted
Tick-borne haemoparasites
Rodents
Ectoparasites
Ticks
Veterinary science theses SDG-03
Veterinary science theses SDG-11
SDG-11: Sustainable cities and communities
SDG-03: Good health and well-being
Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title_full Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title_fullStr Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title_full_unstemmed Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title_short Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area
title_sort occurrence of tick borne haemoparasites in selected south african wild rodent species in the mnisi communal area
topic UCTD
Unrestricted
Tick-borne haemoparasites
Rodents
Ectoparasites
Ticks
Veterinary science theses SDG-03
Veterinary science theses SDG-11
SDG-11: Sustainable cities and communities
SDG-03: Good health and well-being
url http://hdl.handle.net/2263/67985